实用肿瘤学杂志 ›› 2014, Vol. 28 ›› Issue (6): 530-534.doi: 10.11904/j.issn.1002-3070.2014.06.010

• 论著 • 上一篇    下一篇

肺癌患者体内组织瞬间平移和旋转对立体定向放射治疗摆位的影响

上官志毅, 胡洪涛, 陈林, 董文雷   

  1. 哈尔滨医科大学附属肿瘤医院放射治疗技术中心(哈尔滨 150040)
  • 收稿日期:2014-06-09 出版日期:2014-12-28 发布日期:2015-01-08
  • 通讯作者: 胡洪涛,E-mail:huht9099@sohu.com
  • 作者简介:上官志毅,男,(1986-),本科,技师,从事放射治疗工作的研究

Translational and rotational intra-and inter-fractional errors in patient and target position during the influence of the setup

SHANG GUAN Zhiyi,HU Hongtao,CHEN Lin,DONG Wenlei   

  1. Radiation Therapy Technology Center,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150040,China
  • Received:2014-06-09 Online:2014-12-28 Published:2015-01-08

摘要:

目的 在体部立体定向放射治疗(SBRT)中,利用锥形束CT(CBCT)比较软组织匹配及骨解剖匹配的精度,评估组织内部和组织之间瞬间平移在肺癌病人肿瘤中心位置的旋转误差,实现在线校正。方法 选用美国瓦里安公司的具有机载影像系统(On-borad-imager,OBI)的clinac-ix直线加速器治疗机治疗的肺癌患者8例。通过CBCT对SBRT每位患者治疗前后进行比较,评价体内组织瞬间的平移和旋转导致患者体位和肿瘤中心位置数值的变化。结果 骨解剖匹配和软组织匹配的区别在于体位变化是3.0mm(0~8.3mm),病人的肿瘤位置变化是1.4mm(0~12.2mm)和2.2mm(0~13.2mm)。这个中心偏移中位数是2.2mm(0~4.7mm),其余系统误差和随机误差约1°。结论 在肺癌的立体SBRT的转换改进治疗过程中,肿瘤中心位置的改变主要是受机体内部组织瞬间平移和旋转所影响。

关键词: 体部立体定向放射治疗, 摆位误差, 肺肿瘤

Abstract:

Objective In the body of stereotactic radiotherapy(SBRT),using Cone Beam is the matching precision of soft tissue and bone anatomy,translation between evaluation organization and internal organization in the rotation of the lung cancer patients with tumor location error,location correction.Methods Application varian companies in the United States has the airborne imaging system clinac-ix linear accelerator apparatus treatment of 8 cases of lung cancer patients.By CBCT and SBRT comparison before and after the treatment for each patient and evaluate internal instant translation and rotation of the body of the patients with SBRT postures,tumor location and tumor center of baseline shift score changes.Results Based on the difference between of the anatomy of the bone and soft tissue match position is 3.0mm(0~8.3mm).The patient′s tumor location in 3-d median change is 1.4mm(0~12.2mm)and 12.2 mm(0~13.2mm).The median baseline offset between 3 d score is 2.2 mm(0~4.7mm).The rest of the system error and random error about 1 °.Conclusion In Lung cancer SBRT transformation to improve treatment of lung tumor process,change the position of tumor center is mainly affected by the body′s internal organization instant translation and rotation.

Key words: Stereotactic body radiotherapy, Setup errors, Lung cancer

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