实用肿瘤学杂志 ›› 2014, Vol. 28 ›› Issue (6): 553-556.doi: 10.11904/j.issn.1002-3070.2014.06.015

• 综述 • 上一篇    下一篇

卵巢癌术前新辅助化疗筛选与评估的展望

宋雨霖综述, 王晶审校   

  1. 哈尔滨医科大学附属肿瘤医院妇三科(哈尔滨 150081)
  • 收稿日期:2014-06-25 出版日期:2014-12-28 发布日期:2015-01-08
  • 通讯作者: 王晶,E-mail:wj6507@163.com
  • 作者简介:宋雨霖,女,(1988-),硕士研究生,从事妇科肿瘤临床的研究

The screening and assessment of the neoadjuvant chemotherapy for the ovarian cancer

SONG Yulin,WANG Jing   

  1. Department of Gynaecology,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China
  • Received:2014-06-25 Online:2014-12-28 Published:2015-01-08

摘要:

卵巢癌是妇科恶性肿瘤致死率最高的肿瘤。肿瘤细胞减灭术辅以术后铂类为主的联合化疗是目前公认的卵巢癌标准治疗方案。但对于就诊时已属晚期且伴发高危疾病,无法直接手术的患者,术前的新辅助化疗(Neoadjuvant chemotherapy,NACT)的应用显示出了优越性,并得到了临床医生的肯定且已应用于晚期恶性肿瘤的治疗中。值得探讨的是:哪些患者在初次治疗时宜选用新辅助化疗,而不是直接行肿瘤细胞减灭术。本文对近年来的相关研究进行了归纳总结,希望对临床医生的决策有所帮助。

关键词: 晚期卵巢癌, 新辅助化疗, 评估, 筛选标准

Abstract:

Ovarian cancer is the highest death rate of gynecologic malignant tumor.Currently,people recognize standard treatment for ovarian cancer was that reduction-Tumor cells of platinum based chemotherapy after surgery.But for those patients who have developed into advanced cancer that cannot be operated the surgeries directly,the application of preoperative Neoadjuvant chemotherapy(NACT)does have the superiority.which is recognized by the majority of clinical doctors,and has been widely used in the treatment of advanced malignant tumor.It is worthy to discussing which part of patients should choose the initial treatment of Neoadjuvant chemotherapy,rather than a direct treatment of destroying tumor cells.This article is summarizing the empirical cases based on related research,in order to help clinicians to make a decision on the treatment of ovarian cancer.

Key words: Advanced ovarian cancer, Neoadjuvant chemotherapy, Assessment, Screening criteria

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