实用肿瘤学杂志 ›› 2015, Vol. 29 ›› Issue (3): 259-262.doi: 10.11904/j.issn.1002-3070.2015.03.015

• 综述 • 上一篇    下一篇

非小细胞肺癌放化疗后局部复发再程放疗的研究进展

吕研1, 李文鑫1, 李剑1综述, 徐向英1,2审校   

  1. 1.哈尔滨医科大学附属肿瘤医院(哈尔滨 150081);
    2.黑龙江省肿瘤防治研究所
  • 收稿日期:2014-11-26 出版日期:2015-06-28 发布日期:2015-06-25
  • 通讯作者: 徐向英 E-mail:xuxxyy@sohu.com
  • 作者简介:吕研,男,(1984-),硕士研究生,从事肺癌放射治疗的相关研究
  • 基金资助:

    1.黑龙江省对外科技合作项目(WB12C101);2.哈尔滨市科技创新人才研究专项基金(2012RFXXS063)

Progresses on reirradiation for locally recurrence of non-small-cell lung cancer patients after radiotherapy and chemotherapy

LV Yan1,LI Wenxin1,LI Jian1,XU Xiangying1,2   

  1. 1.The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China;
    2.Heilongjiang Provincial,Institute for Tumor Treatment and Prevention
  • Received:2014-11-26 Online:2015-06-28 Published:2015-06-25

摘要:

非小细胞肺癌放化疗后的复发率较高,再程治疗的主要手段是放疗、化疗及放化综合治疗等。其治疗目的在于提高局部控制率的同时延长生存期。再程放疗对于治疗局部复发的非小细胞肺癌是可行的,治疗方法安全,能较好地提高患者生活质量。大多数患者可以耐受,有良好的近期疗效,未见严重的近期放射性损伤,但是晚期放射性损伤及远期疗效尚有待进一步研究。本文就非小细胞肺癌放化疗后局部复发再程放疗的作用及其相关临床研究进展进行综述。

关键词: 癌症, 非小细胞肺, 复发, 再程放疗

Abstract:

The recurrence rate of non-small cell lung cancer(NSCLC)patients after radiotherapy and chemotherapy have been increasing.The therapy scheme consists of reirradiation、chemotherapy、and chemoradiotherapy,with the purpose of improving the local control and prolonging the survival time.Reirradiation is feasible for locally recurrence of non-small-cell lung cancer patients,treatment is security and could better improve quality of life in patients.The majority of patients are tolerable and have better short-term efficacy,No severe short term radiation induced injury is observed.But the long term radiation induced injury and long term efficacy need further investigation.In the present paper,we review the roles of reirradiation for locally recurrence of non-small-cell lung cancer patients after radiotherapy and chemotherapy and the progress in clinical research.

Key words: Carcinoma, Non-small cell lung, Recurrent, Reirradiation

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