实用肿瘤学杂志 ›› 2015, Vol. 29 ›› Issue (4): 364-367.doi: 10.11904/j.issn.1002-3070.2015.04.017

• 综 述 • 上一篇    下一篇

肿瘤多药耐药机制的研究进展

张伟 综述,吴瑾 审校   

  1. 哈尔滨医科大学附属肿瘤医院(哈尔滨 150081)
  • 收稿日期:2015-01-16 出版日期:2015-08-27 发布日期:2015-08-27
  • 通讯作者: 吴瑾 E-mail:w.u_jin@163.com
  • 作者简介:张伟,女(1988-),硕士研究生,从事肿瘤内科的研究
  • 基金资助:
    黑龙江省教育厅2013年度科学技术项目(12531243)

The research progress on cancer multidrug resistance mechanisms

ZHANG Wei,WU Jin   

  1. The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China
  • Received:2015-01-16 Online:2015-08-27 Published:2015-08-27

摘要: 肿瘤多药耐药已成为肿瘤化疗成功与否的关键因素之一,因此克服肿瘤多药耐药是肿瘤治疗的当务之急。肿瘤多药耐药机制是一个十分复杂的过程,受多种因素影响。因此,对肿瘤多药耐药机制进行深入研究将有助于筛选出更加合适的抗肿瘤药物。本文就近年来肿瘤多药耐药机制的研究进展做一综述。

关键词: 肿瘤, 多药耐药, 机制

Abstract: The multidrug resistance(MDR)has become one of the key factors in the success of chemotherapy.Thus,overcoming multidrug resistance of tumor has become a pressing matter of the moment for tumor therapy.The mechanism of MDR is a very complicated process,influenced by many factors.Therefore,the tumor multidrug resistance mechanisms in depth study will help to select more appropriate anti-tumor drugs.In this review,we described about MDR mechanisms researching progress in recent years.

Key words: Cancer, Multidrug resistance, Mechanism

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