实用肿瘤学杂志 ›› 2015, Vol. 29 ›› Issue (5): 385-389.doi: 10.11904/j.issn.1002-3070.2015.05.001

• 论著 •    下一篇

Logistic回归模型在超声评价甲状腺结节良恶性及淋巴转移的应用研究

冯卓颖1, 鹿瑶1, 苏雁欣2, 都杨3   

  1. 1.黑龙江省农垦总局总医院(哈尔滨 150088);
    2.哈尔滨医科大学附属第二医院;
    3.哈尔滨医科大学国家卫生计生委病因流行病学重点实验室
  • 收稿日期:2015-06-10 出版日期:2015-10-28 发布日期:2015-10-30
  • 通讯作者: 都杨,E-mail:hrbmudy@126.com
  • 作者简介:冯卓颖,女(1985-),硕士,主治医师,从事超声诊断工作的研究
  • 基金资助:
    黑龙江省卫生厅科研课题(2013-133)

Logistic regression model for ultrasonic evaluation of thyroid nodule benign and malignancy and lymphatic metastasis

FENG Zhuoying1, LU Yao1, SU Yanxin2, DU Yang3   

  1. 1.The General Hospital of Heilongjiang Land Reclamation Bureau,Harbin 150088,China;
    2.The Second Affiliated Hospital of Harbin Medical University;
    3.Key Lab of Etiology and Epidemiology,Ministry of Health,Harbin Medical University
  • Received:2015-06-10 Online:2015-10-28 Published:2015-10-30

摘要: 目的 应用Logistic回归模型,筛选出甲状腺恶性结节的超声影像学特征危险因素。方法 240例甲状腺结节患者经超声检查,并手术治疗有明确病理诊断的患者纳入本研究,将术前结节的超声特征引入Logistic回归模型,筛选甲状腺恶性结节的超声影像学特征危险因素。结果 经过Logistic逐步回归模型分析,筛选出纵横比≥1、微钙化、低回声是甲状腺癌患病的影响因素。本次研究同时发现微钙化可做为预测甲状腺癌淋巴转移的危险因素。结论 超声医生可以在临床诊断中,参考本研究筛选出的危险因素作为诊断甲状腺恶性结节及转移的辅助指标。在未来,前瞻性的更大规模的同类研究仍有必要。

关键词: 甲状腺结节, 甲状腺癌, Logistic回归, 淋巴结转移

Abstract: Objective To explore the ultrasonic imaging features of malignant thyroid nodules risk factors by logistic regression.Methods Two hundreds and forty patients with thyroid nodules by ultrasonic examination and surgical treatment for patients with definited pathological diagnosis were included in this study.The preoperative sonographic features of the nodules were put into the logistic regression model to explore the risk factors of ultrasonic imaging features of malignant thyroid nodules.Results By logistic regression model analysis,hypoecho,taller than wide ≥1 and micro calcification were found to be significantly statistical variables for thyroid carcinoma.Micro calcification could predict thyroid cancer for lymph node metastases.Conclusion During clinical diagnosis,hypoecho,taller than wide more than 1 and micro calcification could be used as indicators by ultrasound doctors to judge malignant thyroid nodules and lymph node metastases.Prospective larger similar research is still very necessary to explore the indicator for thyroid carcinoma in the future.

Key words: Thyroid nodule, Thyroid carcinoma, Logistic regression, Lymphatic metastasis

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