实用肿瘤学杂志 ›› 2018, Vol. 32 ›› Issue (4): 344-348.doi: 10.11904/j.issn.1002-3070.2018.04.012

• 综述 • 上一篇    下一篇

中国人群食管鳞癌生存分析研究新进展

杜灵彬1,2 综述, 魏文强1 审校   

  1. 1.国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院(北京 100021);
    2.浙江省肿瘤医院/浙江省癌症中心
  • 收稿日期:2018-05-15 出版日期:2018-08-20 发布日期:2018-09-06
  • 通讯作者: 魏文强,E-mail:weiwq@cicams.ac.cn
  • 作者简介:杜灵彬,男,(1980-),在读博士,副研究员,从事肿瘤流行病学的研究
  • 基金资助:
    国家重点研发计划项目(编号:2016YFC0901405);浙江省自然科学基金(编号:LY15H260001)

Progress research in survival analysis of esophageal squamous cell carcinoma(ESCC)in Chinese population

DU Lingbin1,2,WEI Wenqiang1   

  1. 1.National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100021,China;
    2.Zhejiang Cancer Hospital/Zhejiang Cancer Center
  • Received:2018-05-15 Online:2018-08-20 Published:2018-09-06

摘要: 我国食管癌整体负担较重,鳞癌是我国食管癌最主要的病理类型,占比超过85%。当前我国食管癌人群生存率的研究存在诸多局限,需要以人群为基础的多中心大样本研究来提供属于我国食管鳞癌生存率等预后指标的信息,验证国外已有证据并在中国发现新特征。人群为基础的高精度生存分析能提供代表性的生存率结果,反映某一地区食管癌整体预后水平,为制定和优化食管癌防治策略提供可靠依据;也可为探索和验证影响食管癌治疗效果的潜在因素提供代表性资料,从而进一步优化临床治疗策略。本文总结了近年来我国在食管癌生存率、预后因素等方面的研究进展,并与国际进行比较,以期为后续研究提供依据。

关键词: 食管癌, 鳞状细胞癌, 生存率, 预后, 中国

Abstract: The overall burden of esophageal cancer in China is still relatively serious.Esophageal squamous cell carcinoma(ESCC)is the most important pathological type of esophageal cancer in China,accounting for more than 85%.At present,there are still many limitations on the study of the survival rate of esophageal cancer in China.It is necessary to provide information on the prognostic indicators such as the survival rate of ESCC in China based on the multi-center large-sample study to verify the existing evidence abroad and discover new features in China.The population based high-precision survival analysis can provide representative survival results,reflecting the overall prognosis of esophageal cancer in a certain area and also supply a reliable basis for the development and optimization of esophageal cancer prevention and treatment strategies.This analysis can also explore and verify the effects of esophageal cancer treatment to underly factors which provide representative material to further optimize clinical treatment strategies.This article summarizes the research progress in the survival rate and prognosis factors of esophageal cancer in China in recent years,and compares it with the international other countries,in order to provide a basis for follow-up research.

Key words: Esophageal cancer, Squamous cell carcinoma, Survival rate, Prognosis, China

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