实用肿瘤学杂志 ›› 2013, Vol. 27 ›› Issue (1): 85-87.doi: 10.3969/j.issn.1002-3070.2013.01.019

• 综述 • 上一篇    下一篇

葡萄糖调节蛋白78在肿瘤中的研究进展

吉天舒1, 王丹2综述, 刘宝刚1审校   

  1. 1.哈尔滨医科大学附属第三医院内一科(哈尔滨 150081);
    2.哈尔滨市道外区人民医院内二科
  • 收稿日期:2012-02-03 出版日期:2013-02-28 发布日期:2013-03-07
  • 通讯作者: 刘宝刚, E-mail:liubaogang1962@sina.com
  • 作者简介:吉天舒, 女, (1986-), 硕士研究生, 从事肿瘤内科研究

The reaserch progression of Glucose Regulated Protein78 in the tumor

JI Tianshu1, WANG Dan2, LIU Baogang1   

  1. 1.Department of Internal Medicine, The Third Affiliated Hospital of Harbin Medical University, Harbin 150081, China;
    2.Department of Medicine, RenMin hospital in DaoWai district of Harbin
  • Received:2012-02-03 Online:2013-02-28 Published:2013-03-07

摘要: 葡萄糖调节蛋白78(GRP78)作为一种内质网分子伴侣, 与肿瘤的发生、发展十分密切, GRP78在肿瘤组织中有较高的表达, 促进肿瘤细胞的增长与转移。有实验证实, GRP78的表达水平可以作为预测肿瘤预后的指标, 并在探索肿瘤的治疗中有一定的参考意义。

Abstract: GRP78 as an endoplasmic reticulum molecular chaperones has been found to be assoiated with tumorigenesis.GRP78 has high expression in tumortissues, which promoting the growth and metastasis of tumor.Expression of GRP78 may become an index to predict tumor prognosis.It has significance in the treatment of tumor.

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