Abstract: Resveratrol is a natural polyphenol compound, existing in grapes and other plants, which is regard as phytoalexin.Res has various biological activity of pharmacology of ant-tumor effect, cardiovascular protection, ant-inflammatory effect and so on, but it has no side effects on healthy cells.Res especially has a great effect on tumor cells, which mainly activates apoptosis inducing factor(suchas:TRAIL, Caspase-3, Bax and so on)of tumor cells.Res also can change the tumor cell cycle′ s proportion, via p21 blocks the G₀/G₁ period, Achieve anti-tumor effects.Our article aims to make a review on the latest research on Res′ anti-tumor effect.