PRACTICAL ONCOLOGY JOURNAL ›› 2015, Vol. 29 ›› Issue (3): 245-248.doi: 10.11904/j.issn.1002-3070.2015.03.012

• Reviews • Previous Articles     Next Articles

Present situation and advances on the nimotuzumab related radiosensitivity research

TENG Kai1,2,ZHANG Yong1,LIU Li1   

  1. 1.Cancer Center,Wuhan Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;
    2.Hainan Cancer Hospital
  • Received:2015-01-04 Online:2015-06-28 Published:2015-06-25

Abstract:

With data support from abundant research,epithelial growth factor receptor(EGFR)signaling pathway is associated with radiotherapy resistance.EGFR inhibition has become one of Methods to increase radiosensitivity.As the first EGFR monoclonal antibody developed by China and Cuba,nimotuzumab demonstrates its distinct clinical characteristics and has been extensively explored in head and neck cancer,esophageal cancer,high grade glioma.This article mainly reviews the present situation and recent advances on the radiosensitivity research of nimotuzumab.

Key words: Nimotuzumab, Radiosensitivity, Cancer

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