PRACTICAL ONCOLOGY JOURNAL ›› 2016, Vol. 30 ›› Issue (6): 568-571.doi: 10.11904/j.issn.1002-3070.2016.06.019

• Review • Previous Articles     Next Articles

Research progress of MUC1 and MUC16 in gallblader carcinoma

ZHU Tong,TAO Xuanchen,SUN Shibo   

  1. Department of General Surgery,The Second Affiliated Hospital of Harbin Medical University,Harbin 150001,China
  • Received:2016-06-03 Online:2016-12-31 Published:2016-12-27

Abstract: Mucins(MUC)are secreted by the epithelial cells of polymer,the height of glycosylation glycoprotein,widely existing in the respiratory system,digestive system,urogenital system in the mucosa epithelium and mucus secretion.The resent studies show that sticks are closely associated with tumor protein family.Among them,the sticky protein 1(CA153)and 16 mucins(CA125)has been confirmed that the abnormal expression in the bile duct carcinoma.However,there is unclear relationship between the development,invasion,metastasis and prognosis of gallbladder.Based on the retrospective literature at home and abroad in recent years,the research progress on the sticky protein 1 and mucins 16 in the gallbladder is summarized in the present review.

Key words: MUC1, MUC16, Gallbladder carcinoma, Tumor marker

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