PRACTICAL ONCOLOGY JOURNAL ›› 2017, Vol. 31 ›› Issue (6): 564-568.doi: 10.11904/j.issn.1002-3070.2017.06.016

• Review • Previous Articles     Next Articles

The application of PET/MRI in high-grade glioma by radiotherapy

ZHAO Yongrui, XU Jiankun   

  1. Department of Radiation Oncology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China
  • Received:2017-01-17 Online:2017-12-28 Published:2018-01-02

Abstract: Regulation of calcineurin 1(RCAN1),as an endogenous protein that interacts with calcineurin(CaN),widely expresses in many malignant tumor cells,such as small cell lung cancer,thyroid cancer,leukemia,liver cancer,malignant glioma,endometrial adenocarcinoma and so on.In recent years,many studies have been shown that when RCAN1 is highly expressed,it can inhibit tumor proliferation,differentiation,invasion and metastasis by a variety of ways,thereby inhibiting tumor progression.These findings play an important role in the survival and prognosis of patients,and provide a theoretical basis for the treatment and intervention of malignant tumors.

Key words: High-grade glioma, Positron emission tomography, Magnetic resonance imaging, Radiotherapy

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