Abstract: Objective The of this study was to investigate the relationship between the molybdenum target imaging features and clinical signs of mammography,and the expression of HER-2 receptor in breast cancer patients with positive receptors of estrogen and progesterone.Methods One hundred and eleven patients with estrogen and progesterone receptor-positive breast cancer who were admitted to our hospital from July to September 2017 were examined with mammography before operation.Immunohistochemical analysis was performed on breast cancer tissues.Pathological features and features related to mammography were analyzed after operation.The relationship between clinicopathological features and mammography-related signs,and HER-2 expression was also analyzed statistically.Results Of the 111 patients,34 were HER-2 positive patients.There were significant difference between the observed indicators and the over-expression of HER-2(P＜0.05).These indicators included lymph node metastasis,calcification of the mass,margin of the mass,the shape of calcification,and the blood status of vessels.The mammography of patients with triple positive breast cancer is more likely to manifest as lymph node enlargement,mass with calcification or simple calcification,marginal burrs,granular calcification,and vascular thickening.Conclusion The expression of HER-2 in breast cancer patients with positive estrogen and progesterone receptors can be reflected to some extent by lymph node metastasis,tumor with calcification,tumor margin,calcification,calcification morphology and peripheral blood vessel thickening.In terms of clinical conditions,The biological behavior and characteristics of tumor can be inferred based on the clinicopathological features of the patient and the imaging findings of the mammography,providing a direction for the treatment and evaluation of prognosis in breast cancer patients.

Key words: Breast cancer, Molybdenum target, HER-2