PRACTICAL ONCOLOGY JOURNAL ›› 2019, Vol. 33 ›› Issue (1): 73-77.doi: 10.11904/j.issn.1002-3070.2019.01.013

• Review • Previous Articles     Next Articles

Progress in Wnt signaling pathway and tumorigenesis

DING Jiexian1,2, ZHANG Jin1,2, CHEN Yonggang2, WANG Xingwen1,2, WANG Shuanke2   

  1. 1.Department of Orthopaedics,Second Hospital of Lanzhou University,Lanzhou 730000,China;
    2.Key Laboratory of Orthopedics of Gansu Province
  • Received:2018-06-06 Online:2019-02-28 Published:2019-02-13

Abstract: The Wnt/beta-catenin signaling pathway plays an important role in tumorigenesis and development,and is a key pathway mediating carcinogenesis.Therefore,further studies of Wnt/beta-catenin signaling pathway may provide powerful help for exploring the pathogenesis of tumors and seeking effective diagnosis and therapy.This article reviews the research progress of Wnt/beta-catenin signaling pathway and tumorigenesis.

Key words: Tumors, Wnt signaling pathway, Cancer therapy

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