Journal of Practical Oncology ›› 2019, Vol. 33 ›› Issue (4): 380-383.doi: 10.11904/j.issn.1002-3070.2019.04.018

• Review • Previous Articles    

Advance of whole brain radiotherapy irradiation of hippocampus in the treatment of small cell lung cancer

ZHU Shijia, XU Xiangying   

  1. 1.Department of Chest Radiotherapy,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2018-11-23 Published:2019-08-30

Abstract: About 15% to 20% of patients with small cell lung cancer(SCLC)have brain metastases at the time of initial diagnosis,and more than 80% of patients eventually develop brain metastases.Whole brain radiotherapy(WBRT)is the standard treatment for brain metastases in lung cancer.Whole brain prophylactic irradiation(PCI)is an effective treatment for preventing brain metastases in SCLC.With the improvement of treatment technology and the standard of treatment,the survival of SCLC patients is prolonged.The use of spiral tomography(TOMO)technology for hippocampal-protected WBRT in PCI or brain metastasis can reduce neurocognitive impairment and improve the life quality of patient.

Key words: Small cell lung cancer, Whole brain radiotherapy, Prophylactic carnial irradiation, Hippocampal protection

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