PRACTICAL ONCOLOGY JOURNAL ›› 2013, Vol. 27 ›› Issue (5): 476-479.doi: 10.3969/j.issn.1002-3070.2013.05.023

• Review • Previous Articles    

Platelet-derived growth factor and its receptor:potential molecular targets for gastric cancer

LI Tao1,LI Sha2   

  1. 1.536 hospital of PLA,Xining 810007,China
    2.Lanzhou General Hospital of PLA
  • Received:2013-02-25 Online:2013-10-28 Published:2013-10-15

Abstract: Platelet-derived growth factor and its receptor have been found to play an important role in cancer initiation,angiogenesis,apoptosis as well as inhibition of tumor stromal pressure.Recently,their inhibitors have specific effects on gastric cancer,which can inhibit angiogenesis,enhance therapeutic effect and reduce tumor growth and lymphatic metastasis in gastric cancer.In the present paper,we made a review of its inhibitors in treatment of gastric cancer.

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