肿瘤相关中性粒细胞的研究进展

doi:10.11904/j.issn.1002-3070.2017.04.015

Abstract

Abstract: Tumor growth depends on the tumor microenvironment(TME).Tumor-associated neutrophils(TANs)are important inflammatory cells in TME.TANs are divided into“N1”type with anti-tumor effect and“N2”type of tumor-promoting effect.Therefore,TANs have both beneficial and harmful aspects of the body.A large number of studies have been shown that TANs affect tumor formation,metastasis,angiogenesis and immune response,regulated by the secretion of cytokines and chemokines.This review will summarize the biological characteristics of TANs,and tumor development,prognosis and treatment of tumor as well as research progress of the relationship between TANs and tumor.

Key words: Tumor-associated neutrophils(TANs), Tumor microenvironment(TME), Tumor

CLC Number:

R730.2

QIN Qi,XU Yang,ZHAO Hong,ZHANG Qingyuan. Research progress of tumor-associated neutrophils[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(4): 367-370.

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Research progress of tumor-associated neutrophils

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