Journal of Practical Oncology ›› 2022, Vol. 36 ›› Issue (6): 580-584.doi: 10.11904/j.issn.1002-3070.2022.06.017

• Review • Previous Articles    

Research progress of stereotactic body radiotherapy combined with targeted drugs in metastatic renal cell carcinoma

LI Hao, ZHANG Heqian, GAO Jianing, TENG Lichen   

  1. Department of Urology,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2022-07-18 Revised:2022-10-09 Online:2022-12-28 Published:2023-01-06

Abstract: Stereotactic body radiotherapy(SBRT)is a breakthrough in radiotherapy in recent years.It has the advantages of high fractionated dose,high biological effect and less segmentation times,which can significantly improve the radiosensitivity of renal cell carcinoma.Molecular targeted therapy has greatly extended the progression-free survival and overall survival of some patients,but systemic drug resistance is inevitable in most cases.In recent years,the combination of SBRT and targeted drugs in the treatment of metastatic renal cell carcinoma has initially shown its effectiveness and safety,which may become a more effective treatment scheme.This article reviews the research progress in the treatment of metastatic renal cell carcinoma with SBRT combined with targeted drugs.

Key words: Metastatic renal cell carcinoma, Stereotactic body radiotherapy, Targeted drugs

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