关键词: 宫颈癌, 危险因素, 病例对照研究

Abstract: Objective To evaluate the risk factors related to the incidence of cervical cancer through a case-control study on the the comparison of cervical cancer patients in Shenyang with local residents in Shenyang.Methods In reference to the patients with cervical cancer hospitalized in Liaoning Tumor Hospital from Shenyang,1000 residents living in Ertaizi Street,Dadong District,Shenyang were randomly selected for the screening of cervical cancer and its precancerous lesions,the epidemiological investigations and the collections of HPV samples and cervical smear samples.The obtained data put into SPSS 13.0 statistical software to make the analysis of single-factor χ² analysis,logistic regression analysis and multi-factor logistic regression analysis.Results HPV positive(OR=221.62,95%CI:28.53~1721.51),the first sex life younger than 21 years old(OR=6.65,95%CI:1.88~23.51)is the risk factors of Cervical cancer;condom(OR=0.05,95%CI:0.01~0.18)is the protect factor of Cervical cancer.Conclusion It is of great significance to remove HPV infection,advocate the use of condoms,establish a scientific concept of sexual life and avoid early sexual experience in reducing the incidence of cervical cancer in Shenyang.

Key words: Cervical cancer, Risk factor, Case-control study