实用肿瘤学杂志 ›› 2023, Vol. 37 ›› Issue (5): 429-433.doi: 10.11904/j.issn.1002-3070.2023.05.007

• 综述 • 上一篇    下一篇

脂肪酸代谢与卵巢癌

樊婷婷1, 丁丹妮1, 赵子雪1, 于洋2 综述, 韩凤娟2 审校   

  1. 1.黑龙江中医药大学研究生院(哈尔滨 150040);
    2.黑龙江中医药大学附属第一医院
  • 收稿日期:2022-05-21 修回日期:2023-01-23 出版日期:2023-10-28 发布日期:2024-03-18
  • 通讯作者: 韩凤娟,E-mail:hanfengjuan2004@163.com
  • 作者简介:樊婷婷,女,(1998-),硕士研究生,从事中西医结合治疗妇科肿瘤的研究。
  • 基金资助:
    国家自然科学基金面上项目(编号:82074484)

Fatty acid metabolism and ovarian cancer

FAN Tingting1, DING Danni1, ZHAO Zixue1, YU Yang2, HAN Fengjuan2   

  1. 1. Graduate School,Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China;
    2. The First Affiliated Hospital,Heilongjiang University of Traditional Chinese Medicine
  • Received:2022-05-21 Revised:2023-01-23 Online:2023-10-28 Published:2024-03-18

摘要: 卵巢癌是女性生殖系统中常见的恶性肿瘤,其发病和调控机制极其复杂,至今尚不明确。脂肪酸代谢主要涵盖脂肪酸摄取、合成、氧化过程。既往研究表明,脂肪酸代谢在卵巢癌的发生发展中发挥独特的作用,因此本综述回顾了现有文献,深入探讨脂肪酸代谢与卵巢癌之间的相关性,旨在为卵巢癌的脂肪酸代谢机制和靶向治疗提供新的视角和思考。

关键词: 卵巢癌, 脂肪酸代谢, 酶, 靶向治疗

Abstract: Ovarian cancer is a common malignant tumor in the female reproductive system, and its pathogenesis and regulatory mechanisms are extremely complex and still unclear. Fatty acid metabolism mainly involves the processes of fatty acid uptake, synthesis, and oxidation. Previous studies have shown that fatty acid metabolism plays a unique role in the occurrence and development of ovarian cancer. Therefore, this article reviews existing literature and delves into the correlation between fatty acid metabolism and ovarian cancer, aiming to provide new perspectives and reflections on the mechanism of fatty acid metabolism and targeted treatment of ovarian cancer.

Key words: Ovarian cancer, Fatty acid metabolism, Enzymes, Targeted therapy

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