实用肿瘤学杂志 ›› 2025, Vol. 39 ›› Issue (2): 80-85.doi: 10.11904/j.issn.1002-3070.2025.02.002

• 癌情监测 • 上一篇    下一篇

2008—2019年连云港市食管癌发病与死亡情况及趋势分析

柴莉莉, 李伟伟, 董建梅, 秦绪成, 张伟伟, 相璐, 仲玮, 王威, 马昭君   

  1. 连云港市疾病预防控制中心慢病科(连云港 222003)
  • 收稿日期:2024-06-05 修回日期:2025-02-17 出版日期:2025-04-28 发布日期:2025-05-06
  • 通讯作者: 马昭君,E-mail:55664671@qq.com
  • 作者简介:柴莉莉,女,(1988—),本科,主管医师,从事慢性非传染性疾病防制相关研究。
  • 基金资助:
    江苏省卫生计生委预防医学科研课题(编号:Y2015030)

Analysis of the incidence and mortality of esophageal cancer and its trend in Lianyungang city from 2008 to 2019

CHAI Lili, LI Weiwei, DONG Jianmei, QIN Xucheng, ZHANG Weiwei, XIANG Lu, ZHONG Wei, WANG Wei, MA Zhaojun   

  1. Department of Chronic Disease,Lianyungang Center for Disease Control and Prevention,Lianyungang 222003, China
  • Received:2024-06-05 Revised:2025-02-17 Online:2025-04-28 Published:2025-05-06

摘要: 目的 分析连云港市2008—2019年食管癌发病与死亡情况及变化趋势。方法 将连云港市所有肿瘤登记地区食管癌数据汇总整理并质控达标,计算发病率、死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、0~74岁累计率、35~64岁截缩率和顺位等指标。使用Joinpoint 4.7.0.0软件分析食管癌中标发病率和中标死亡率的平均年度变化百分比(average annual percentage change,AAPC)。结果 2008—2019年连云港市食管癌的发病率为25.90/10万,中标发病率为17.95/10万,世标发病率为17.91/10万,位居恶性肿瘤发病谱第3位。死亡率为20.55/10万,中标死亡率为13.86/10万,世标死亡率为13.71/10万,位居恶性肿瘤死亡谱第3位。食管癌的发病率、死亡率、中标率、世标率均为男性高于女性,且农村地区高于城市地区。2008—2019年连云港市食管癌的发病和死亡变化趋势相同,呈下降趋势,中标发病率的AAPC为-6.19%(95% CI:-7.08%~-5.30%,P<0.001),中标死亡率的AAPC为-4.03%(95% CI:-5.81%~-2.22%,P<0.001),分性别、城乡食管癌的中标发病率和中标死亡率均呈现下降趋势(P<0.05),其中城市女性食管癌的中标发病率和中标死亡率的下降幅度最大,平均每年分别下降-7.99%(95% CI:-10.86%~-5.03%,P<0.001)和-9.19%(95% CI:-12.35%~-5.93%,P<0.001)。结论 连云港市食管癌的发病和死亡水平均呈现下降趋势,农村地区和男性群体是食管癌的重点防控人群。

关键词: 食管癌, 发病率, 死亡率, 趋势, 连云港市

Abstract: Objective The aim of this study was to analyze the incidence and mortality of esophageal cancer and its trend in Lianyungang city from 2008 to 2019. Methods The data of esophageal cancer in all cancer registry areas in Lianyungang city were collected and sorted out,and the quality control reached the standards.The incidence,mortality,age-standardized rate of Chinese population(ASRC),age-standardized rate of World population(ASRW),cumulative rate at 0-74 years old,truncation rate of 35-64 years old,and composition ranking were calculated.The Joinpoint 4.7.0.0 software was used to analyze the average annual percentage change(AAPC)of the age-standardized incidence and mortality of esophageal cancer by the standard population(ASIRC and ASMRC). Results From 2008 to 2019,the incidence of esophageal cancer in Lianyungang city was 25.90/100,000,ASIRC was 17.95/100,000,ASIRW was 17.91/100,000,ranking the third in the incidence spectrum of malignant tumors.The mortality was 20.55/100,000,ASMRC was 13.86/100,000,and ASMRW was 13.71/100,000,ranking the third in the malignant tumor mortality spectrum.The incidence,mortality,ASIRC and ASMRC of esophageal cancer were higher in men than those in women,and higher in rural areas than those in urban areas.From 2008 to 2019,the change trend of incidence and mortality of esophageal cancer in Lianyungang city was the same,showing a downward trend.The AAPC of the ASIRC was-6.19%(95% CI:-7.08%-5.30%,P<0.001),and the AAPC of the ASMRC was -4.03%(95% CI:-5.81%-2.22%,P<0.001).Among them,the ASIRC and ASMRC of esophageal cancer in urban and rural areas showed a downward trend(P<0.05).Among them,the ASIRC and ASMRC of esophageal cancer in urban women decreased the most,with an average annual decline of-7.99%(95% CI:-10.86%-5.03%,P<0.001)and-9.19%(95% CI:-12.35%-5.93%,P<0.001). Conclusion The incidence and mortality of esophageal cancer in Lianyungang city have shown a downward trend,a rural areas and male populations are the key prevention and control populations for esophageal cancer.

Key words: Esophageal cancer, Incidence, Mortality, Trend, Lianyungang city

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