2016—2020年辽宁省肿瘤登记地区淋巴瘤发病与死亡情况及其变化趋势分析

doi:10.11904/j.issn.1002-3070.2025.05.004

实用肿瘤学杂志 ›› 2025, Vol. 39 ›› Issue (5): 388-392.doi: 10.11904/j.issn.1002-3070.2025.05.004

2016—2020年辽宁省肿瘤登记地区淋巴瘤发病与死亡情况及其变化趋势分析

任方晗¹, 祝天岑¹, 礼彦侠¹, 陈丽莉², 那军¹, 田园梦¹, 穆慧娟¹

1.辽宁省疾病预防控制中心慢性非传染性疾病预防控制所(沈阳 110173);
2.营口市疾病预防控制中心慢性非传染性疾病防制科

收稿日期:2024-12-26 修回日期:2025-03-08 出版日期:2025-10-28 发布日期:2025-11-07
通讯作者: 穆慧娟,E-mail:incdcmhj@163.com
作者简介:任方晗,女,(1997—),学士,公共卫生医师,从事慢性病预防与控制的研究。

Analysis of the incidence and mortality of lymphoma in cancer registration areas of Liaoning Province from 2016 to 2020 and their changing trends

REN Fanghan¹, ZHU Tiancen¹, LI Yanxia¹, CHEN Lili², NA Jun¹, TIAN Yuanmeng¹, MU Huijuan¹

1. Department of Chronic Disease Prevention and Control,Liaoning Center for Disease Control and Prevention,Shenyang 110173,China;
2. Department of Chronic Disease Prevention and Control,Yingkou Center for Disease Control and Prevention

Received:2024-12-26 Revised:2025-03-08 Online:2025-10-28 Published:2025-11-07

摘要/Abstract

摘要： 目的分析2016—2020年辽宁省肿瘤登记地区淋巴瘤发病与死亡状况及其变化趋势,为淋巴瘤防治工作提供数据支持。方法收集并整理2016—2020年辽宁省肿瘤登记地区数据,计算淋巴瘤粗发病率、粗死亡率、中标发病率、中标死亡率、世标发病率、世标死亡率和累积率等指标;采用Joinpoint 5.0.2软件分析2016—2020年上述指标的变化趋势。结果 2016—2020年辽宁省肿瘤登记地区淋巴瘤粗发病率为7.43/10万,中标发病率4.07/10万,世标发病率3.95/10万;粗死亡率为4.29/10万,中标死亡率2.07/10万,世标死亡率2.02/10万。男性中标发病率和中标死亡率(4.62/10万、2.53/10万)均高于女性(3.56/10万、1.61/10万),城市地区中标发病率和死亡率(4.65/10万、2.32/10万)均高于农村(2.46/10万、1.65/10万)。淋巴瘤发病率和死亡率均随年龄增长而上升,发病率在70~79岁年龄组达到高峰,死亡率在80+岁组达到高峰。2016—2020年淋巴瘤粗发病率由6.86/10万上升至8.22/10万,变化趋势有统计学意义(APC=5.06%,95% CI:1.13%~9.14%,P=0.026);中标发病率由4.01/10万上升至4.45/10万,变化趋势无统计学意义(P＞0.05)。粗死亡率由3.85/10万上升至4.53/10万,中标死亡率由2.02/10万下降至2.01/10万,二者变化趋势均无统计学意义(P＞0.05)。结论辽宁省肿瘤登记地区淋巴瘤中标发病率与死亡率均呈现男性高于女性、城市高于农村的特征,且在老年组达到高峰。应加强对重点人群的防控与健康管理,尤其关注老年人群的健康需求,并探索多学科协作诊疗的可能方向,以减轻疾病负担。

关键词: 淋巴瘤, 发病率, 死亡率, 趋势分析, 辽宁省

Abstract: Objective The aim of this study was to analyze the incidence and mortality of lymphoma and their changing trends in cancer registration areas of Liaoning Province from 2016 to 2020,and to provide data support for lymphoma prevention and treatment. Methods The data of tumor registration areas in Liaoning province from 2016 to 2020 were collected and sorted out,and the crude incidence,mortality,China standardized incidence and mortality,world standardized incidence and mortality,and cumulative rate of lymphoma were calculated;Joinpoint 5.0.2 software was used to analyze the changing trends of the above indicators from 2016 to 2020. Results From 2016 to 2020,the crude incidence of lymphoma in tumor registration areas of Liaoning Province was 7.43/100,000,age-standardized incidence by Chinese standard population(ASIRC)was 4.07/100,000,and age-standardized incidence by world standard population(ASIRW)was 3.95/100,000;the crude mortality was 4.29/100,000,age-standardized mortality by Chinese standard population(ASMRC)was 2.07/100,000,and age-standardized mortality by world standard population(ASMRW)was 2.02/100,000.The ASIRC and ASMRC were higher in males(4.62/100,000 and 2.53/100,000,respectively)than in females(3.56/100,000 and 1.61/100,000,respectively),also higher in urban areas(4.65/100,000 and 2.32/100,000,respectively)than in rural areas(2.46/100,000 and 1.65/100,000,respectively).The incidence and mortality of lymphoma increased with age.The incidence reached its peak in the 70-79 age group,and the mortality reached its peak in the 80+ age group.From 2016 to 2020,the crude incidence of lymphoma increased from 6.86/100,000 to 8.22/100,000,with a statistically significant trend(APC=5.06%,95% CI:1.13%-9.14%,P=0.026).ASIRC increased from 4.01/100,000 to 4.45/100,000,with no statistical significance(P＞0.05). The crude mortality increased from 3.85/100,000 to 4.53/100,000,while ASMRC decreased from 2.02/100,000 to 2.01/100,000,with no statistically significant trend in the two changes(P＞0.05). Conclusions The incidence and mortality of lymphoma in cancer registration areas of Liaoning Province are higher in men than those of women,and higher in cities than those in rural areas,and reach the peak in the elderly group.The prevention and control of key populations and health management should be strengthened,especially pay attention to the health needs of the elderly population,and explore possible directions for multidisciplinary collaborative diagnosis and treatment to reduce the disease burden.

Key words: lymphoma, incidence, mortality, trend analysis, Liaoning Province

中图分类号:

R733

任方晗, 祝天岑, 礼彦侠, 陈丽莉, 那军, 田园梦, 穆慧娟. 2016—2020年辽宁省肿瘤登记地区淋巴瘤发病与死亡情况及其变化趋势分析[J]. 实用肿瘤学杂志, 2025, 39(5): 388-392.

REN Fanghan, ZHU Tiancen, LI Yanxia, CHEN Lili, NA Jun, TIAN Yuanmeng, MU Huijuan. Analysis of the incidence and mortality of lymphoma in cancer registration areas of Liaoning Province from 2016 to 2020 and their changing trends[J]. Journal of Practical Oncology, 2025, 39(5): 388-392.

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2016—2020年辽宁省肿瘤登记地区淋巴瘤发病与死亡情况及其变化趋势分析

Analysis of the incidence and mortality of lymphoma in cancer registration areas of Liaoning Province from 2016 to 2020 and their changing trends

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