长链非编码RNA CCAT1与消化系统恶性肿瘤关系的研究进展

doi:10.11904/j.issn.1002-3070.2019.04.015

Abstract

Abstract: Long non-coding RNAs(lncRNAs)is a functional RNA molecule with a sequence length greater than 200 nucleotides that is not translated into a protein.LncRNA is of great value in the clinical application of malignant tumors and is closely related to the diagnosis,prevention,treatment and prognosis of tumors.CCAT1(human colon cancer associated transcript-1)can play a carcinogenic role by promoting cell proliferation,invasion and migration.CCAT1 can be used as a biomarker for tumor prognosis.In this review,the research progress on the relationship between CCAT1 and digestive system malignant tumors is reviewed in recent years,the current status and prospects of malignant tumor treatment by CCAT1 are discussed.

Key words: CCAT1, Long noncoding RNA, Digestive system cancer, Cancer biomarker

CLC Number:

R735

ZHAO Jinlu, LI Guodong, LIU Ming. Advanced in the relation between long-chain non-coding RNA CCAT1 and digestive system malignancies[J]. Journal of Practical Oncology, 2019, 33(4): 367-370.

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Advanced in the relation between long-chain non-coding RNA CCAT1 and digestive system malignancies

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