Wnt信号通路与非小细胞肺癌发生发展关系的研究进展

doi:10.11904/j.issn.1002-3070.2016.01.014

Abstract

Abstract:

Wnt signaling pathway participates in the physiological process of cell growth,differentiation,migration and apoptosis.Its abnormal activation is closely related to the tumorigenesis and progression.Wnt signaling is also known to regulate the process of proliferation,angiogenesis,adhesion,invasion and metastasis of tumor cells in non-small-cell lung cancer.There are a lot of members in Wnt signaling pathway and their expression levels affect the prognosis of non-small-cell lung cancer.It plays an instructive role in the individualized treatment of non-small-cell-lung cancer to lucubrate the relation between Wnt signaling pathway and the tumorigenesis and progression of non-small-cell lung cancer.

Key words: Wnt signaling pathway, Non-small-cell lung cancer, β-catenin, Tumorigenesis, Prognosis

CLC Number:

R734.2

WANG Daquan, ZHAO Lujun, WANG Ping. Research on the progress of the relation between Wnt signaling pathway and the tumorigenesis and progression of non-small-cell lung cancer[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(1): 66-70.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2016.01.014

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2016/V30/I1/66

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Research on the progress of the relation between Wnt signaling pathway and the tumorigenesis and progression of non-small-cell lung cancer

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