Abstract: Objective The aim of this study was to analyze the current status of incidence and mortality of brain tumors in 2015 and the trend of changes from 2006 to 2015 in Jiangsu province. Methods The data year 2015 from 35 cancer registries collected and quality-controlled from Jiangsu provincial center for disease control and prevention in 2018 were used and data of brain tumor were extracted to calculate the incidence(mortality)of urban and rural,gender and age groups,and the Chinese population standard estimating the incidence and mortality of brain tumors in the province based on indicators such as the conversion rate(abbreviated as Chinese standard rate),the World population standardized rate(abbreviated as the World standard rate),the cumulative incidence or mortality(0~74 years old)and other indicators.Combined with the demographic data,the incidence and mortality of brain tumors in the whole province were estimated.The province′s tumor registration data from 2006 to 2015 were summarized,sorted out,and calculated the average annual change percentage(AAPC)of the standardized incidence and mortality in the past 10 years by Joinpoint software. Results In 2015,the province′s cancer registry covered a total of 38,761,144 people(15,168,594 people in urban areas,and 23,592,550 people in rural areas).The mortality to incidence ratio of brain tumors was 0.67,proportion of morphological cerification was 41.42%,and proportion of death cerification only was 1.46%.It is estimated that the number of new cases of brain tumors in the province was 5,452,the crude incidence was 7.16/100,000,the Chinese standard rate was 4.79/100,000,the World standard rate was 4.79/100,000,and the cumulative incidence of 0~74 years old was 0.51%.It is estimated that there were 2,446 new cases of brain tumors in urban areas,and the Chinese standard rate was 4.99/100,000;the estimated new cases of brain tumors in rural areas are 3 006,and the Chinese standard rate was 4.65/100,000.The province′s estimated brain tumor deaths were 3,626 cases,the crude mortality was 4.76/100,000,the Chinese standard rate was 3.09/100,000,the World standard rate was 3.13/100,000,and the cumulative mortality rate between 0 and 74 years old was 0.32%.There were 1,429 deaths from brain tumors in urban areas,and the Chinese standard rate was 2.86/100,000;there were 2,197 deaths from brain tumors in rural areas,and the Chinese standard rate was 3.27/100,000.The Chinese standard rate of brain tumor incidence in urban areas and women showed a significant upward trend,with an average annual increase of 1.918% and 3.149%.The Chinese standard rate of brain tumor mortality in rural areas as a whole and in women showed a significant downward trend,with an average annual decrease of 1.587% and 1.882%. Conclusion Brain tumors are common malignant tumors in my country,and early screening,prevention and control of brain tumors should be strengthened.

Key words: Brain tumor, Incidence, Mortality, Cancer registry, Trend