Abstract: Objective The objective of this study was to investigate the morbidity,mortality characteristics and prevalence trends of lung cancer in the tumor registration areas of Yunnan province from 2011 to 2016,and to provide suggestion for the prevention and treatment of lung cancer. Methods The incidence and death cases of lung cancer in the tumor registration areas of Yunnan province from 2011 to 2016 were collected and sorted out.The incidence,mortality,standardized incidence,standardized mortality,the cut-off rate,the cumulative rate(0-74 years old),and annual percentage of trend change(annual percentage change,APC)of lung cancer were analyzed. Results The crude incidence of lung cancer in Yunnan cancer registration areas from 2011 to 2016 was 42.05/100,000,the China standard rate was 28.38/100,000,the World standard rate was 28.21/100,000,the cumulative rate(0~74 years old)was 3.48%,and the truncated age-standardized rate was 55.38/100,000.The male incidence was 58.52/100,000,the China standard rate was 40.53/100,000,and the female incidence was 25.11/100,000,the China standard rate was 16.62/100,000.The incidence in urban areas was 44.14/100,000,the China standard rate was 28.11/100,000,and the incidence in urban area was 39.40/100,000,the China standard rate was 29.02/100,000.The mortality of lung cancer in Yunnan cancer registration areas from 2011 to 2016 was 33.16/100,000,the China standard rate was 28.33/100,000,the World standard rate was 21.64/100,000,the cumulative rate(0~74 years old)was 2.61%,and the truncated age-standardized rate was 38.96/100,000.The male mortality was 47.47/100,000,the China standard rate was 32.32/100,000.The female mortality was 18.44/100,000,the China standard rate was 11.71/100,000.The mortality in urban areas was 34.54/100,000,the China standard rate was 21.28/100,000,and the mortality in rural areas was 31.47/100,000,the China standard rate was 22.81/100,000.The age-specific incidence and mortality rate were at a low level in the 0-34 years old group,and increased rapidly after 35-years old group.There was no statistical significant difference between the total number of lung cancer and the trend of incidence in urban areas and rural areas from 2011 to 2016(P＞0.05),but the annual percent change in incidence of lung cancer among women in rural areas was 10.6%,and the annual percent change in standardized incidence was 9.8%.The crude incidence and standardized incidence of women in rural areas showed an upward trend(P＜0.05). Conclusion The incidence and mortality of lung cancer in Yunnan cancer registration areas from 2011 to 2016 were generally lower than that in the national and the western regions,and the annual change in incidence and mortality of rural women showed an upward trend.It is recommended to continue to expand the coverage of early diagnosis and treatment of lung cancer,and actively carry out tobacco control activities.

Key words: Cancer registration, Lung cancer, Incidence, Mortality, Time trend, Yunnan