热休克蛋白90在食管鳞癌中的表达及临床意义

doi:10.11904/j.issn.1002-3070.2021.06.017

Abstract

Abstract: Esophageal squamous cell carcinoma(ESCC)is the main pathological type of esophageal carcinoma in China.It is characterized by an insidious onset,rapid metastasis,and rapid drug resistance during treatment,resulting in an unsatisfactory prognosis.Many downstream proteins regulated by heat shock protein 90(HSP90)are involved in cell proliferation and other processes,so they often play an important role in the occurrence and development of malignant tumors.More and more studies have confirmed that HSP90 is highly expressed in a variety of malignant tumors and can affect tumor resistance.In recent years,the exploration relevant role of HSP90 in ESCC has also yielded many achievements worthy of attention.This article will review the expression and clinical significance of HSP90 in ESCC.

Key words: Esophageal squamous cell carcinoma, Heat shock protein 90, Heat shock protein inhibitors

CLC Number:

R735.1

MENG Di, XU Qianwen, SUN Xiuwei. Expression and clinical significance of heat shock protein 90 in esophageal squamous cell carcinoma[J]. Journal of Practical Oncology, 2021, 35(6): 572-575.

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Expression and clinical significance of heat shock protein 90 in esophageal squamous cell carcinoma

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