Donghe Sandstone was deposited in the early stage of sea transgression from the end of Devonian to the early stage of Carboniferous, Donghe sandstone is not an isochronous stratum with various depositional ages in different areas. As a kind of broadly-developed deposits in the early stage of transgress, Donghe sandstone has an outstanding feature of fill and level up. The important controls of the development of depositional facies are the transgress speed, the sediment supply and the pre-transgression paleo-relief. In northern Tarim Basin, blocked by the Tabei paleo-uplift, seawater stayed around the paleo-uplift for a long period, which, combined with the coarse-grained sediment supply, promoted the development of shore beach deposits. In central Tarim Basin, however, the deposit types are diversiform with the complex topography background. Fluvial deposits developed in the bottom conglomerate section, and estuary and shore beach deposits in the massive sandstone section and the sandy conglomerate section. Different section has its own characteristics of grain component, grain selectivity and grain size. While in the other gently-slope and flat areas, rapidly-deposited shore and shelf sediments developed during the transgressive period. Controlled by the depositional environment, the effective reservoir of Donghe Sandstone distribute regionally. Beside the depositional factor, the low paleo-geothermal gradient and the short-term deep-burial history are the other two crucial controls of the development of the high-quality Donghe Sandstone reservoir.