18F-FDG PET/CT对不明原因腹腔积液的临床应用价值

doi:10.11904/j.issn.1002-3070.2016.02.004

实用肿瘤学杂志 ›› 2016, Vol. 30 ›› Issue (2): 114-117.doi: 10.11904/j.issn.1002-3070.2016.02.004

¹⁸F-FDG PET/CT对不明原因腹腔积液的临床应用价值

陆佩欧, 王文志, 李迎辞, 刘蕊, 胡玉民, 于丽娟

哈尔滨医科大学附属肿瘤医院PET/CT中心(哈尔滨 150081)

收稿日期:2016-01-28 出版日期:2016-04-28 发布日期:2016-04-28
通讯作者: 于丽娟,E-mail:yulijuan2003@126.com
作者简介:陆佩欧,男,(1979-),硕士,主治医师,从事PET/CT肿瘤学诊断的研究
基金资助:
黑龙江省卫生厅科研课题(2013077)

The clinical value of ¹⁸F-FDG PET/CT for the patients with ascites of unknown causes

LU Pei′ou, WANG Wenzhi, LI Yingci, LIU Rui, HU Yumin, YU Lijuan

Center of PET/CT,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China

Received:2016-01-28 Online:2016-04-28 Published:2016-04-28

摘要/Abstract

摘要： 目的探讨¹⁸F-FDG PET/CT对不明原因腹腔积液的临床应用价值。方法分析106例以腹腔积液为首发症状、并行¹⁸F-FDG PET/CT以明确积液良恶性的资料,¹⁸F-FDG PET/CT判定结果采用两种方法:(1)PET/CT(定位)法:PET/CT诊断结果完全取决于腹膜上¹⁸F-FDG摄取情况,若是摄取增高则为恶性,同机CT只作为解剖定位;(2)PET/CT(形态)法:PET/CT结果需结合腹膜的CT形态学改变和PET上¹⁸F-FDG摄取情况进行综合分析。结果 PET/CT(定位)鉴别腹腔积液良恶性的敏感性、特异性、准确性分别为90.2%、71.1%、82.1%,而PET/CT(形态)的敏感性、特异性、准确性分别为95.1%、93.3%、94.3%,原发灶检出率为85.2%。PET/CT(形态)的特异性和准确性高于PET/CT(定位)(P=0.002、P＜0.001),两者之间敏感性无统计学差别(P=0.250)。结论在腹腔积液良恶性鉴别方面,PET/CT(形态)比PET/CT(定位)更具有临床应用价值,¹⁸F-FDG PET/CT(形态)对恶性腹腔积液原发灶检出具有重要意义。

关键词: 腹腔积液, 正电子发射型体层摄影术, 体层摄影术

Abstract: Objective To assess the clinical value of ¹⁸F-FDG PET/CT for the patients with ascites of unknown causes.Methods A total of 106 patients with ascites undergoing ¹⁸F-FDG PET/CT examination was retrospectively studied and ¹⁸F-FDG PET/CT imaging was interpreted by two ways.(1)PET/CT(localization):Diagnostic Results of PET/CT depended on the degree of ¹⁸F-FDG uptake in peritoneum with CT was trecoted as anatomical localization,and high ¹⁸F-FDG uptake in peritoneum was regarded as malignancy.(2)PET/CT(morphology):Morphological changes of peritoneum on CT imaging and the degree of ¹⁸F-FDG uptake on PET imaging were simultaneously considered when interpreting the diagnostic Results of PET/CT.Results In the differential diagnosis of ascites of unknown cause,the sensitivity,specificity and accuracy of PET/CT(localization)were 90.2%,71.1% and 82.1%,respectively.These values of PET/CT(morphology)were 95.1%,93.3% and 94.3%,and 85.2% of malignant ascites were found primary lesion.The specificity and accuracy of PET/CT(morphology)were higher than those of PET/CT(localization)(P=0.002,P＜0.001).Statistical difference was not found in both sensitivities.Conclusion PET/CT(morphology)had higher clinical value than PET/CT(localization)in the differential diagnosis of ascites with unknown cause,and had important significance in detecting primary cause of malignant ascites.

Key words: Ascites, Positron emission tomography, Tomography

中图分类号:

R735.5

陆佩欧, 王文志, 李迎辞, 刘蕊, 胡玉民, 于丽娟. ¹⁸F-FDG PET/CT对不明原因腹腔积液的临床应用价值[J]. 实用肿瘤学杂志, 2016, 30(2): 114-117.

LU Pei′ou, WANG Wenzhi, LI Yingci, LIU Rui, HU Yumin, YU Lijuan. The clinical value of ¹⁸F-FDG PET/CT for the patients with ascites of unknown causes[J]. PRACTICAL ONCOLOGY JOURNAL, 2016, 30(2): 114-117.

参考文献

1 Kleinberg L,Holth A,Fridman E,et a1.The diagnostic role of claudins in serous effusions[J].Am J Clin Pathol,2007,127(6):928-937.
2 克力木,张成,陈勇,等.腹腔镜腹腔探查诊断不明原因腹水价值探讨[J/CD].中华临床医师杂志:电子版,2010,4(12):2542-2545.
3 东雷,郑成竹,胡旭光,等.腹腔镜对不明原因腹水诊断价值研究[J].中国实用外科杂志,2007,27(8):627-629.
4 王丽娟,王全师,陈萍,等.¹⁸F-FDG PET/CT显像鉴别腹腔积液性质的价值[J].中华核医学与分子影像杂志,2012,32(2):105-110.
5 王峰智.¹⁸F-FDG PET/CT 显像在不明原因腹腔积液患者积液性质鉴别诊断中的作用[J].医学前沿,2012(30):315-316.
6 陈素芸,傅宏亮,马超,等.¹⁸F-FDG PET/CT对腹腔积液良恶性的诊断价值[J].放射免疫学杂志,2012,25(5):524-525.
7 熊灿,周力,陈晓琴.PET/CT显像对不明原因腹水的诊断价值[J].贵州医药,2012,36(12):1140-1142.
8 Zhang M,Jiang XF,Zhang M,et al.The role of ¹⁸F-FDG PET/CT in the evaluation of ascites of undetermined origin[J].J Nucl Med,2009,50(4):506-512.
9 Rubini G,Altini C,Notaristefano A,et al.Role of ¹⁸F-FDG PET/CT in diagnosing peritoneal carcinomatosis in the restaging of patient with ovarian cancer as compared to contrast enhanced CT and tumor marker Ca-125[J].Rev Esp Med Nucl Imagen Mol,2014,33(1):22-27.
10 Bamba Y,Itabashi M,Kameoka S.Clinical use of PET/CT in peritoneal carcinomatosis from colorectal cancer[J].Hepatogastroenterology,2012,59(117):1408-1411.
11 王晓燕,饶良俊,陈志丰,等.PET-CT与腹部增强CT对腹膜转移瘤诊断价值的对比分析[J].中华胃肠外科杂志,2012,15(7):702-705.
12 王颖,李亚明,尹雅芙,等.¹⁸F-FDG PET/CT对检出恶性腹腔积液患者原发癌灶的临床价值[J].中国医学影像技术,2012,28(12):2193-2196.

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¹⁸F-FDG PET/CT对不明原因腹腔积液的临床应用价值

The clinical value of ¹⁸F-FDG PET/CT for the patients with ascites of unknown causes

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