肺结核与肺癌相互影响的研究进展

doi:10.11904/j.issn.1002-3070.2018.04.011

摘要/Abstract

摘要： 肺结核与肺癌都严重危害着人类健康,结核病目前发病率和死亡率居高不下,而肺癌是全世界范围内最常见的死亡率较高的恶性肿瘤之一,两种疾病预后不同,但是二者从发病的原因上讲却是相互影响的,结核病慢性炎症刺激、结核分枝杆菌磷酸酶成分以及结核分枝杆菌感染引发的免疫反应都可导致肺癌的发生。肺癌发生后不恰当的治疗方式也会有利于结核分枝杆菌生长,导致肺结核的发生。面对这样全球性的重大公共卫生问题,我们将用近年来的流行病学调查和实验研究结果为两种疾病的共存阐明原因,也将为下一步结核病合并肺癌患者的治疗提供依据。

关键词: 肺结核, 肺癌, 结核分枝杆菌

Abstract: Both tuberculosis and lung cancer are seriously damaging to human health.Tuberculosis is currently at high morbidity and mortality,and lung cancer is one of the most common malignant tumors in the world.The prognosis of two diseases is different,but the causes of two diseases are mutual influence.The chronic inflammatory stimulation of tuberculosis,the phosphatase components of mycobacterium tuberculosis and the immune response induced by mycobacterium tuberculosis infection can cause lung cancer.Inappropriate treatment after lung cancer can also contribute to the growth of mycobacterium tuberculosis.Faced with such a global major public health problem,the epidemiological investigations and experimental results are used to clarify the reasons for the coexistence of two diseases in recent years.The evidence will provide a basis for the treatment of patients with tuberculosis and lung cancer.

Key words: Tuberculosis, Lung cancer, Mycobacterium tuberculosis

中图分类号:

R378.91

魏静, 陶媛美慧, 付英梅, 赵吉子, 张文莉, 张凤民. 肺结核与肺癌相互影响的研究进展[J]. 实用肿瘤学杂志, 2018, 32(4): 340-343.

WEI Jing,TAO Yuanmeihui,FU Yingmei,ZHAO Jizi,ZHANG Wenli,ZHANG Fengmin. Research progress in the interaction between pulmonary tuberculosis and lung cancer[J]. PRACTICAL ONCOLOGY JOURNAL, 2018, 32(4): 340-343.

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