海马区保护治疗小细胞肺癌全脑照射的研究进展

doi:10.11904/j.issn.1002-3070.2019.04.018

摘要/Abstract

摘要： 小细胞肺癌(SCLC)患者中约15%~20%初诊时已有脑转移,超过80%的患者最终会发展成为脑转移。全脑放疗(WBRT)是肺癌脑转移的标准治疗。全脑预防性照射(PCI)是预防SCLC脑转移的有效治疗手段。随着治疗技术的提高和治疗手段的规范,SCLC患者生存期的延长,采用螺旋断层放疗(TOMO)技术海马保护的WBRT用于PCI或脑转移患者,能够降低神经认知功能损伤,提高患者生活质量。

关键词: 小细胞肺癌, 全脑放疗, 全脑预防性照射, 海马保护

Abstract: About 15% to 20% of patients with small cell lung cancer(SCLC)have brain metastases at the time of initial diagnosis,and more than 80% of patients eventually develop brain metastases.Whole brain radiotherapy(WBRT)is the standard treatment for brain metastases in lung cancer.Whole brain prophylactic irradiation(PCI)is an effective treatment for preventing brain metastases in SCLC.With the improvement of treatment technology and the standard of treatment,the survival of SCLC patients is prolonged.The use of spiral tomography(TOMO)technology for hippocampal-protected WBRT in PCI or brain metastasis can reduce neurocognitive impairment and improve the life quality of patient.

Key words: Small cell lung cancer, Whole brain radiotherapy, Prophylactic carnial irradiation, Hippocampal protection

中图分类号:

R734.2

朱诗佳徐向英. 海马区保护治疗小细胞肺癌全脑照射的研究进展[J]. 实用肿瘤学杂志, 2019, 33(4): 380-383.

ZHU Shijia, XU Xiangying. Advance of whole brain radiotherapy irradiation of hippocampus in the treatment of small cell lung cancer[J]. Journal of Practical Oncology, 2019, 33(4): 380-383.

参考文献

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