低剂量螺旋CT肺癌筛查的研究现状与进展

doi:10.11904/j.issn.1002-3070.2020.04.015

摘要/Abstract

摘要： 肺癌是最常见的恶性肿瘤之一,严重影响人民身心健康。在全世界大多数国家,其发病率和死亡率均居首位,因此对肺癌高危人群进行早期筛查的必要性与日俱增。随着低剂量螺旋CT(Low-dose computed tomography,LDCT)在各个国家的推广和应用,肺癌的死亡率明显降低,但同时也带来许多问题,如假阳性过高、过度诊断会造成患者经济和心理的双重负担;女性被动吸烟的人数越来越多,但未被纳入肺癌高危人群的筛查;肺癌筛查对高危人群的定义与标准、阳性结节的定义与标准均尚无统一指南发布等。这些问题日益突出,是现今大多数研究面临的主要困难与挑战。本文就LDCT肺癌筛查的研究现状和进展做一综述。

关键词: 低剂量螺旋CT, 肺癌, 筛查

Abstract: Lung cancer is one of the most common malignant tumors,which seriously affects people's body and mental health.In most countries around the world,its morbidity and mortality rank first,so the necessary for early screening of people at high risk for lung cancer is increasing.With the promotion and application of low-dose computed tomography(LDCT)in various countries,the mortality of lung cancer has been significantly reduced,but at the same time it has also brought many problems,such as high false positives and overdiagnosis,to cause double burden of patient economics and psychology.More and more women are passively smoking,but they are not included in the screening of high-risk lung cancer groups;The screening lung cancer for the definition and standards of high-risk pupolation as well as the definition and standard of positive nodules have not yet been unified guideline release,etc.These issues are becoming increasingly prominent,and today many studies are facing the main difficulties and challenges.This article reviews the research status and progress of LDCT in lung cancer screening.

Key words: Low-dose computed tomography, Lung cancer, Screening

中图分类号:

R734.2

孟瑞瑞, 刘圆圆, 官新立, 周鹏, 许国辉. 低剂量螺旋CT肺癌筛查的研究现状与进展[J]. 实用肿瘤学杂志, 2020, 34(4): 372-376.

MENG Ruirui, LIU Yuanyuan, GUAN Xinli, ZHOU Peng, XU Guohui. Status and progress of low-dose spiral CT in lung cancer screening[J]. Journal of Practical Oncology, 2020, 34(4): 372-376.

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链接本文: http://journal09.magtechjournal.com/Jwk3_syzlxzz/CN/10.11904/j.issn.1002-3070.2020.04.015

http://journal09.magtechjournal.com/Jwk3_syzlxzz/CN/Y2020/V34/I4/372

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