实用肿瘤学杂志 ›› 2009, Vol. 23 ›› Issue (2): 142-142.doi: 10.3969/j.issn.1002-3070.2009.02.011

• 论著 • 上一篇    下一篇

ER、PR、Her-2在乳腺癌中的表达及临床意义

王英丽1,尚立华2,刘素杰2,张阳1,朱丽娜3   

  1. 1.吉林省肿瘤防治研究所(长春 130012);
    2.吉林省肿瘤医院;
    3.吉林省肿瘤防治办公室
  • 收稿日期:2009-03-03 出版日期:2009-04-20 发布日期:2012-02-21
  • 作者简介:王英丽,女,(1970-),硕士,副主任技师,从事肿瘤免疫学治疗研究

Expression of ER,PR,Her-2 in breast cancer and its clinical significance

WANG Yingli1,SHANG Lihua2,LIU Sujie2,ZHANG Yang1,ZHU Lina3   

  1. The Tumor Prevention and Cure Institute of Ji Lin Province
  • Received:2009-03-03 Online:2009-04-20 Published:2012-02-21

摘要: 目的探讨雌激素受体(ER)、孕激素受体(PR)及癌基因Her-2在乳腺癌中的表达及其临床意义。方法 应用免疫组化法检测76例乳腺癌ER、PR、Her-2的表达。结果 ER的表达与TNM分期和淋巴结转移呈负相关;PR的表达与淋巴结转移和TNM分期无相关性;Her-2的表达与淋巴结转移和TNM分期呈正相关。结论 乳腺癌患者ER、Her-2检测可以帮助判断乳腺癌预后。

关键词: 乳腺癌, ER, PR, Her-2

Abstract: Objective To study the expression of estrogen receptor(ER),progestogen receptor(PR)and Her-2 in breast cancer and its clinical significance.Method Expression of ER,PR,Her-2 of 76 breast cancer patients were determined by immunohistochemical staining.Result The expression of ER was negatively correlated with TNM stage and lymph nodes metastasis,The expression of PR was not correlated with TNM stage and lymph nodes metastasis,The expression of Her-2 was positively correlated with TNM stage and lymph nodes metastasis.Conclusion To detect the expression level of ER,PR,Her-2 may help to estimate the prognosis.

Key words: Breast cancer, ER, PR, Her-2

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