实用肿瘤学杂志 ›› 2010, Vol. 24 ›› Issue (2): 120-122.doi: 10.3969/j.issn.1002-3070.2010.02.005

• 论著 • 上一篇    下一篇

脑胶质瘤复发与放射性脑损伤的鉴别诊断

杨丹1, 岳晓琳1, 张晶1, 徐丹1, 姬宏飞2, 付锦1   

  1. 1.哈尔滨医科大学附属第二医院神经内科(哈尔滨 150086);
    2.哈尔滨医科大学肿瘤防治研究所
  • 收稿日期:2010-03-09 出版日期:2010-04-28 发布日期:2015-01-24
  • 通讯作者: 付锦,E-mail:fujin6677@126.com
  • 作者简介:杨丹,女,(1981-),硕士,住院医师,从事神经系统疾病的治疗与研究
  • 基金资助:
    黑龙江省科技攻关项目(GC05C40602)

Clinical differential diagnosis between brain glioma recurrence and radiation-induced brain injury

YANG Dan1, YUE Xiaolin1, ZHANG Jing1, XU Dan1, JI Hongfei2, FU Jin1   

  1. 1.Department of Neurology,The Second Affiliated Hospital of Harbin Medical University,Harbin 150086;
    2.Cancer institute of Harbin Medical University
  • Received:2010-03-09 Online:2010-04-28 Published:2015-01-24

摘要: 目的 探讨胶质瘤复发与放射性脑损伤之间的鉴别诊断方法。方法 选择胶质瘤复发和放射性脑损伤患者33例,获取患者症状和体征等临床资料,均进行MRS检查。结果 胶质瘤复发与放射性脑损伤患者的临床表现基本相同,未见显著性差异;胶质瘤复发患者的Cho/Cr、Cho/NAA比值显著高于放射性脑损伤患者,差异具有统计学意义。结论 MRS检查对于鉴别脑胶质瘤复发与放射性脑损伤存在应用价值。

Abstract: Objective To investigate the differential diagnosis method between brain glioma recurrence and radiation-induced brain injury.Methods 33 patients with glioma recurrence and radiation-induced brain injury were selected,the symptoms and sign data of patients were collected,MRS examination was performed in all patients.Results Glioma recurrence and radiation-induced brain injury patients showed approximately same clinical manifestations,which was no significant difference between two groups;Cho/Cr and Cho/NAA ratios were significantly higher in recurrent glioma than that in radiation injury(P<0.05).Conclusion The results suggest that the MRS examination should be applied to determine glioma recurrence and radiation-induced brain injury.

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