实用肿瘤学杂志 ›› 2012, Vol. 26 ›› Issue (1): 92-96.doi: 10.3969/j.issn.1002-3070.2012.01.019

• 综述与论著 • 上一篇    

探讨影响厄洛替尼治疗晚期非小细胞肺癌预后的因素

杨芳, 王萌, 杨朝阳, 洪璇, 陈公琰   

  1. 哈尔滨医科大学附属第三医院内一科(哈尔滨 150081)
  • 收稿日期:2011-02-22 出版日期:2012-02-28 发布日期:2015-01-08
  • 通讯作者: 陈公琰,E-mail:chengongyan@medmail.com.cn
  • 作者简介:杨芳,女,(1984-),硕士研究生,从事肺癌的临床诊断及治疗

Explore the Prognostic Factors of Advanced NSCLC Patients Treated with Erlotinib

YANG Fang,WANG Meng,YANG Zhaoyang,HONG Xuan,CHEN Gongyan   

  1. Department of Medical Oncology,The Third Affiliated Hospital of Harbin Medical University,Harbin 150081
  • Received:2011-02-22 Online:2012-02-28 Published:2015-01-08

摘要: 目的 探讨影响厄洛替尼治疗晚期非小细胞肺癌预后的临床因素。方法 收集55例厄洛替尼治疗晚期非小细胞肺癌患者的临床资料,分析临床特征与PFS、OS的关系。结果 血清LDH升高及0~1度皮疹是不良预后的独立危险因素。结论 血清LDH水平是否正常与皮疹是否严重是影响厄洛替尼治疗晚期NSCLC患者预后的重要因素。

关键词: 厄洛替尼, 晚期非小细胞肺癌, 预后因素

Abstract: Objective The aim of this study is to explore the prognostic factors of advanced NSCLC patients treated with erlotinib.Methods Clinical characteristics of fifty-five advanced NSCLC patients treated with erlotinib were collected.The association of their clinical characteristics with median progression-free survival time(PFS)and overall survival(OS)was analysed.Results High serum LDH level and grade 0-1 rash were independent risk factors for bad prognostic in patients.Conclusion Serum LDH level and grade of rash are important prognostic factors in advanced Non-small Cell Lung Cancer treated with erlotinib.

Key words: Erlotinib, Advanced Non-small Cell Lung Cancer, Prognostic factor

中图分类号: