实用肿瘤学杂志 ›› 2012, Vol. 26 ›› Issue (1): 82-85.doi: 10.3969/j.issn.1002-3070.2012.01.017

• 综述与论著 • 上一篇    下一篇

非小细胞肺癌靶向治疗研究进展

郎济禄1, 孙贤2   

  1. 1.哈尔滨医科大学附属第二医院胸心外科(哈尔滨 150086);
    2.哈尔滨医科大学附属第三医院内一科
  • 收稿日期:2011-10-19 出版日期:2012-02-28 发布日期:2015-01-08
  • 通讯作者: 孙贤,E-mail:sunshine1d1@126.com
  • 作者简介:郎济禄,男,(1983-),硕士,从事胸心外科的手术治疗

Progress in Targeted Therapies for Non-small Cell Lung Cancer

LANG Jilu1,SUN Xian2   

  1. 1.Department of Cardiothoracic Surgery,The Second Affiliated Hospital of Harbin Medical University,Harbin 150086;
    2.Department of Oncology,The Third Affiliated Hospital of Harbin Medical University,Harbin 150081
  • Received:2011-10-19 Online:2012-02-28 Published:2015-01-08

摘要: 目前肺癌的生物靶向药物抗表皮生长因子受体(Epidermal Growth Factor Receptor,EGFR)已成功地应用于肺癌临床治疗。但肺癌分子生物学机制十分复杂,新的生物靶点药物在临床中的重要作用日益受到关注。本文对上述分子生物学标志物在肺癌治疗中的作用及其相关临床研究进展进行综述。

关键词: 非小细胞肺癌, 靶向治疗, 肿瘤标志

Abstract: Nowadays,targeted therapies for lung cancer have entered into the clinical phase.Anti-epidermal growth factor receptor (EGFR)drugs have been successfully applied in the clinical treatment of lung cancer.Molecular mechanisms of lung cancer are very complex,more and more attention has been focused on some new molecular targets in lung cancer in recent years.In the present paper we review the roles of these new biomarkers in lung cancer therapy and the progress in clinical research.

Key words: Lung cancer, Targeted therapies, EGFR

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