Abstract: Objective To observe the role of Bu Yang Huan Wu Decoction in advanced non small cell lung cancer(NSCLC)with high blood coagulation state.Methods 60 patients were randomly divided into two groups with 30 cases in each.The treatment group was followed by conventional chemotherapy combined with Bu Yang Huan Wu Decoctionin treatment,while the control group was treated conventional chemotherapy with Traditional Chinese Medicine placebo.The contents of observation are platelet,coagulation time,blood rheology,and the life quality in the two groups.Results The treatment group is superior to the control group in the change of hemogram,life quality(P＜0.05).Conclusion Bu Yang Huan Wu Decoctionin can improve blood hypercoagulable state in the patients with advanced NSCLC,and to a certain extent,improve the patients life quality.