Abstract: Objective To select the CT characteristics and clinicalopathological parameters of non-small lung cancer which can reflect the expression of Ki-67、survivin and cyclinA protein.Method 33 cases of lung cancer(squamous carcinoma 11 cases and adenocarcinoma 22 cases)have undergone the scanning of 18F-FDG PET/CT before operation.The relationships between CT features, pathological classification, tumor differentiated types, lymph node metastasis and the expression of Ki-67、survivin and cyclinA which were examined by means of SP immunohistochemical technique.Results The positive rates of Ki-67、survivin and cyclinA protein were 69.70%、84.85% and 45.45% respectively.Significant differences in the positive rate of Ki-67 and cyclinA were found between squamous carcinoma and adenocarcinoma(P=0.031 and P=0.032)and between the size ≥2cm and＜2cm(P=0.025), but not among differentiated types, lymph node metastasis and CT feature of lobulation, thin and short spiculation, spinous protuberance, cavity sign, vessel convergence sign and pleural retraction sign(P＞0.05).The positive rate of cyclinA was also related to vessel convergence sign and pleural retraction sign(P=0.027, P=0.032), but not related to other data(P＞0.05).There were no correlations between the positive rate of survivin and other data.Conclusion The study suggested that the ability of proliferation and the speed of cell cycle of squamous carcinoma were stronger than that of adenocarcinoma.The size of tumor can reflect the stronger ability of proliferation.The pleural retraction sign can reflect the faster cell cycles.