宫颈癌术后容积弧形调强与固定野动态调强放疗技术的剂量学比较

doi:10.11904/j.issn.1002-3070.2017.02.011

实用肿瘤学杂志 ›› 2017, Vol. 31 ›› Issue (2): 152-155.doi: 10.11904/j.issn.1002-3070.2017.02.011

宫颈癌术后容积弧形调强与固定野动态调强放疗技术的剂量学比较

于德洋, 杨姗姗, 云惟康, 冯丽娜, 白彦灵

哈尔滨医科大学附属肿瘤医院放射物理科(哈尔滨 150081)

收稿日期:2016-07-23 出版日期:2017-04-20 发布日期:2017-05-04
通讯作者: 白彦灵,E-mail:baiyl2126@126.com
作者简介:于德洋,男,(1987-),硕士,助理工程师,从事放疗剂量学的研究

Dosimetric comparisons of volumetric modulated arc radiotherapy with fixed field dynamic intensity modulated radiotherapy for postoperative cervical carcinoma

YU Deyang,YANG Shanshan,YUN Weikang,FENG Lina,BAI Yanling

Department of Radiation Physics,Harbin Medical University Cancer Hospital,Harbin 150081,China

Received:2016-07-23 Online:2017-04-20 Published:2017-05-04

摘要/Abstract

摘要： 目的比较宫颈癌术后放疗中容积弧形调强放射治疗(VMAT)与固定野动态调强放射治疗(dIMRT)的靶区剂量分布、危及器官受照剂量及治疗时间,为临床治疗选择放疗技术提供依据。方法选取10例宫颈癌术后患者,在Monaco5.11计划系统中分别对每例患者进行容积弧形调强和7野固定野动态调强放疗计划设计,比较两种技术的靶区和危及器官的剂量分布,机器跳数和治疗时间的差异。结果 VMAT技术靶区的平均剂量为46.86Gy,略高于dIMRT技术的46.68Gy(P＜0.05),直肠的V₁₀,V₂₀和小肠V₃₀受照剂量VMAT比dIMRT技术分别高了0.63%,3.34%和4.14%(P＜0.05),靶区的均匀性、适形度和其他危及器官的受照剂量相比,两者没有统计学意义,机器跳数和治疗时间VMAT比dIMRT计划分别减少13.4%和50.6%(P＜0.05)。结论 VMAT技术与dIMRT技术相比剂量分布相当或略优,机器跳数和治疗时间明显减少,在临床应用上对于宫颈癌术后患者建议使用VMAT技术。

关键词: 宫颈癌, 容积弧形调强, 固定野动态调强

Abstract: Objective The objective of this study was to compare the differences between Volumetric Modulated Arc Radiotherapy(VMAT)and Fixed Field dynamic Intensity Modulated Radiotherapy(dIMRT)in dose distribution of target and organ at risk and treatment time,and to provide basis for clinical treatment.Methods Ten patients with postoperative of cervical carcinoma were selected,VMAT and seven fields dIMRT plans were designed for each patient in Monaco 5.11 planning system.We compared the differences of dose distribution of target and organ at risk,monitor units and treatment time between VMAT and 7dIMRT.Results The average dose of target for VMAT plan(46.86Gy)was higher than that of 7dIMRT plan(46.68Gy)(P＜0.05).The percentage of the V₁₀ and V₂₀ of rectum and the V₃₀ of small intestine in VMAT plan was 0.63%,3.34% and 4.14% higher than that in 7dIMRT plan,respectively(P＜0.05).The conformal index(CI),homogeneity index(HI)of PTV and the other exposure dose of organ at risk for both plans were no significant differences.The average monitor units and treatment time of VMAT plan were 13.4% and 50.6% than that of 7dIMRT plan,respectively(P＜0.05).Conclusion The dose distribution of VMAT plan is better or equal to that of 7dIMRT plan,but the monitor units and treatment time of VMAT plan is decreased significantly,we suggest that VMAT plan should be used for postoperative of cervical carcinoma in clinical.

Key words: Cervical carcinoma, VMAT, dIMRT

中图分类号:

R451

于德洋, 杨姗姗, 云惟康, 冯丽娜, 白彦灵. 宫颈癌术后容积弧形调强与固定野动态调强放疗技术的剂量学比较[J]. 实用肿瘤学杂志, 2017, 31(2): 152-155.

YU Deyang,YANG Shanshan,YUN Weikang,FENG Lina,BAI Yanling. Dosimetric comparisons of volumetric modulated arc radiotherapy with fixed field dynamic intensity modulated radiotherapy for postoperative cervical carcinoma[J]. PRACTICAL ONCOLOGY JOURNAL, 2017, 31(2): 152-155.

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宫颈癌术后容积弧形调强与固定野动态调强放疗技术的剂量学比较

Dosimetric comparisons of volumetric modulated arc radiotherapy with fixed field dynamic intensity modulated radiotherapy for postoperative cervical carcinoma

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