2014-2016年合肥市城市居民肺癌筛查率及筛查结果分析

doi:10.11904/j.issn.1002-3070.2021.03.007

实用肿瘤学杂志 ›› 2021, Vol. 35 ›› Issue (3): 231-236.doi: 10.11904/j.issn.1002-3070.2021.03.007

2014-2016年合肥市城市居民肺癌筛查率及筛查结果分析

魏东华¹, 马艳玲¹, 张娟¹, 尹惠萍¹, 张小鹏², 张愉涵³, 代敏³, 钱立庭¹

1.中国科学技术大学附属第一医院西区/安徽省肿瘤医院(合肥 230031);
2.合肥市疾病预防控制中心;
3.国家癌症中心/中国医学科学院北京协和医学院肿瘤医院

收稿日期:2020-12-07 修回日期:2021-03-05 出版日期:2021-06-28 发布日期:2021-06-22
通讯作者: 钱立庭,E-mail:money2004@sina.com
作者简介:魏东华,男,(1966-),本科,助理研究员,从事肿瘤防治工作的研究。
基金资助:
国家重点研发计划-精准医学专项(编号:2017YFC0907901);国家重大公共卫生服务专项—城市癌症早诊早治项目;肺癌早期发现合作研究(编号:CH-L-043)

Analysis of lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016

WEI Donghua¹, MA Yanling¹, ZHANG Juan¹, YIN Huiping¹, ZHANG Xiaopeng², ZHANG Yuhan³, DAI Min³, QIAN Liting¹

1. West District of The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China/Anhui Provincial Cancer Hospital,Hefei 230031,China;
2. Hefei Center for Disease Control and Prevention;
3. National Cancer Center/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College

Received:2020-12-07 Revised:2021-03-05 Online:2021-06-28 Published:2021-06-22

摘要/Abstract

摘要： 目的分析2014—2016年合肥市城市居民肺癌筛查率及筛查结果,评价肺癌筛查效果。方法采取整群抽样的方法,对合肥市7个区40~69岁常住居民进行癌症危险因素问卷调查和肺癌高危因素评估,对评估出的肺癌高危人群进行胸部低剂量螺旋CT检查。分析肺癌高危人群筛查率和检出率。采用主动随访加被动随访统计确诊肺癌数,计算肺癌发病密度。结果 2014—2016年共完成58 105人的问卷调查和肺癌高危风险评估,评估出肺癌高危12 449人,肺癌高危率为21.43%。共5 646人参加低剂量螺旋CT筛查(筛查参与率为45.35%),检出肺部结节1 540人(结节检出率为27.28%),阳性结节354人(阳性结节检出率为6.27%),疑似肺癌54人(疑似肺癌检出率为0.96%)。评估为肺癌高危者的肺癌发病密度为131.01/10万人年;CT筛查者中检出阳性结节的肺癌发病密度为1 255.36/10万人年;CT筛查者中检出阴性结节的肺癌发病密度为103.12/10万人年。结论低剂量螺旋CT可有效发现肺内结节及相关病变,需进一步完善筛查机制,提高肺癌高危人群筛查率,提高筛查效果及防控水平。

关键词: 肺癌, 筛查, 低剂量螺旋CT, 发病密度, 城市, 合肥

Abstract: Objective The aim of this study was to analyze the lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016,and evaluate the effect on lung cancer screening.Methods A cluster sampling method was used to conduct a cancer risk factor questionnaire survey and an assessment of lung cancer risk factors among permanent residents aged 40~69 years old in seven districts of Hefei city.The chest low-dose spiral computed tomography(LDCT)examination was performed on the assessed high-risk population of lung cancer.The screening rate and detection rate of high-risk population were analyzed.The active follow-up and passive follow-up were used to count the number of confirmed lung cancers and calculate the incidence density of lung cancer.Results A total of 58 105 questionnaires and high-risk assessment of lung cancer were completed from 2014 to 2016,and 12 449 people were assessed at high-risk for lung cancer.The high risk rate of lung cancer was 21.43%.A total of 5 646 people participated LDCT screening(the screening participation rate was 45.35%),1 540 people were detected for lung nodules(the nodule detection rate was 27.28%),354 people were positive for nodules(the positive nodules was 6.27%)and 54 people were suspected of lung cancer(the detection rate of suspected lung cancer was 0.96%).The incidence density of lung cancer in high risk of lung cancer patients was 131.01 per 100 000 person-year.The incidence density of lung cancer with positive nodules in CT screeners was 1 255.36 per 100 000 person-year.The incidence density of lung cancer with negative nodules in CT screeners was 103.12 per 100 000 person-year.Conclusion LDCT can effectively find nodules and related lesions in the lung.It is necessary to further improve the screening mechanism,improve the screening rate of lung cancer in high-risk groups,and improve the screening effect on the level of cancer prevention and control.

Key words: Lung cancer, Screening, Low-dose spiral CT, Incidence density, Urban, Hefei

中图分类号:

R73-31

魏东华, 马艳玲, 张娟, 尹惠萍, 张小鹏, 张愉涵, 代敏, 钱立庭. 2014-2016年合肥市城市居民肺癌筛查率及筛查结果分析[J]. 实用肿瘤学杂志, 2021, 35(3): 231-236.

WEI Donghua, MA Yanling, ZHANG Juan, YIN Huiping, ZHANG Xiaopeng, ZHANG Yuhan, DAI Min, QIAN Liting. Analysis of lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016[J]. Journal of Practical Oncology, 2021, 35(3): 231-236.

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2014-2016年合肥市城市居民肺癌筛查率及筛查结果分析

Analysis of lung cancer screening rate and screening results of urban residents in Hefei from 2014 to 2016

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