关键词: 宫颈癌, 发病率, 死亡率, 肿瘤登记, 甘肃

Abstract: Objective The aim of this study was to analyze the incidence and mortality of cervical cancer in cancer registration areas of Gansu province from 2009 to 2015,and to provide the basis for the development of cervical cancer prevention and treatment strategies.Methods According to the audit methods of National Cancer Registry,data of cervical cancer reported by 10 cancer registration were collected from 2009 to 2015,calculate the crude incidence and crude mortality,ASR China and ASR World.ASR China and ASR World were calculated using the 2000 Chinese standard population age structure and Segi′s World standard population age structure,respectively.Annual percentage change(APC)was calculated using the JoinPoint Regression Program 4.7.0.0.Results From 2009 to 2015,there were 3 454 new cases of cervical cancer in cancer registration areas of Gansu province.The crude incidence rate was 18.75/100 000,the ASR China was 15.81/100 000,and the ASR World was 15.95/100 000.Incidence of the urban area(18.86/100 000)were higher than the rural area(18.34/100 000).There were 2 107 death cases of cervical cancer in cancer registration areas of Gansu province,from 2009 to 2015.The mortality was 11.44/100 000,the ASR China was 10.67/100 000,and the ASR World was 10.81/100 000.Mortality of the urban area(11.51/100 000)was higher than the rural area(11.18/100 000).From 2009 to 2015,the age-specific incidence and age-specific mortality of cervical cancer increased with the increase of age,and the incidence peaked in the 50-year-old group(52.64/100 000),and the mortality peaked in the 80-year-old group(47.29/100 000).The crude incidence and crude mortality rate of cervical cancer in Gansu province showed a decreasing trend from 2009 to 2015(APC=-0.9,P=0.9;APC=-4.3,P=0.5),there was no statistically significant change in trends.After age calibration,the incidence of ASR China and mortality of ASR China showed a decreasing trend(APC=-5.3,P=0.2;APC=-12.9,P=0.1),the trends were not statistically significant.Conclusion Although the incidence and mortality rate of cervical cancer in Gansu province have a decreasing trend,which poses a serious threat to the life and health of middle-aged and elderly women.Health education of cervical cancer prevention knowledge should be carried out actively,and healthy lifestyle should be advocated,so as to realize the effective prevention and control of cervical cancer.

Key words: Cervical cancer, Incidence, Mortality, Cancer registration, Gansu