实用肿瘤学杂志 ›› 2021, Vol. 35 ›› Issue (3): 212-217.doi: 10.11904/j.issn.1002-3070.2021.03.004

• 甘肃省癌情监测专题 • 上一篇    下一篇

2009—2015年甘肃省肿瘤登记地区结直肠癌流性特征及变化趋势分析

朱公建1, 朱奕潼2, 丁高恒1, 王宏宗3, 杜美霞3, 刘玉琴1   

  1. 1.甘肃省肿瘤医院(兰州 730050);
    2.纽约大学;
    3.甘肃中医药大学
  • 收稿日期:2021-02-23 修回日期:2021-04-25 出版日期:2021-06-28 发布日期:2021-06-22
  • 通讯作者: 朱公建,E-mail:30796076@qq.com
  • 作者简介:朱公建,男,(1980-),博士研究生,副研究员,从事肿瘤分子流行病学的研究。
  • 基金资助:
    兰州市人才创新创业项目(编号:2018-RC-96)

Analysis for characteristics and trends of colorectal cancer in Gansu cancer registry areas,2009—2015

ZHU Gongjian1, ZHU Yitong2, DING Gaoheng1, WANG Hongzong3, DU Meixia3, LIU Yuqin1   

  1. 1. Gansu Cancer Hospital,Lanzhou 730050,China;
    2. New York University;
    3. Gansu University of Chinese Medicine
  • Received:2021-02-23 Revised:2021-04-25 Online:2021-06-28 Published:2021-06-22

摘要: 目的 了解2009—2015年甘肃省肿瘤登记地区居民结直肠癌发病与死亡情况及其变化趋势,为结直肠癌的防治策略提供依据与建议。方法 收集整理2009—2015年甘肃省11个肿瘤登记处结直肠癌的发病、死亡资料(ICD-10编码为C18-20),按年龄、性别、年份分别统计结直肠癌发病(死亡)率、中标发病(死亡)率、世标发病(死亡)率、年龄别发病(死亡)率、累积率等,运用Joinpoint 4.7.0.0软件计算年度变化百分比(APC)。结果 2009—2015年甘肃省肿瘤登记地区居民结直肠癌新发病例6 903例,发病粗率为18.24/10万,中标发病率为16.51/10万,世标发病率为18.97/10万;结直肠癌死亡病例1 940例,死亡率为11.12/10万,中标死亡率为9.57/10万,世标死亡率为11.81/10万;男性结直肠癌发病率和死亡率(20.49/10万和12.50/10万)均高于女性(15.87/10万和9.68/10万),城市地区结直肠癌发病率和死亡率均高于农村地区;2009—2015年甘肃省结直肠癌发病率和死亡率总体呈下降趋势(APC=-8.9,t=-3.0,P<0.05;APC=-0.9,t=-0.3,P=0.8),发病率变化趋势有统计学意义,死亡率变化趋势无统计学意义。结论 甘肃省结直肠癌发病率和死亡率较高,应加大对结直肠癌高危人群评估,实施早期筛查,以降低结直肠癌发病率和死亡率。

关键词: 结直肠癌, 发病率, 死亡率, 变化趋势, 肿瘤登记, 甘肃

Abstract: Objective The aim of this study was to understand the trends of incidence and mortality of colorectal cancer in Gansu cancer registry areas from 2009 to 2015,and to provide the opinions and suggestions for prevention and treatment strategies of colorectal cancer.Methods The data of colorectal cancer(ICD-10 code for C18-20)were collected from 11 cancer registries in Gansu province from 2009 to 2015.The incidence(mortality),the Chinese standard incidence(mortality),the World standard incidence(mortality),the age-specific incidence(mortality),and the cumulative rate stratified by age,gender and years were analyzed.The Joinpoint Regression program 4.7.0.0 was used to calculate the annual percentage change(APC).Results There were 6 903 new cases of colorectal cancer diagnosed from 2009 to 2015 in Gansu cancer registry areas.The crude incidence was 18.24/100 000,the Chinese standard incidence was 16.51/100 000,and the World standard incidence was 18.97/100 000.There were 1 940 deaths of colorectal cancer reported from 2009 to 2015.The crude mortality was 11.12/100 000,the Chinese standard mortality was 9.57/100 000,and the World standard mortality was 11.81/100 000.Males had higher incidence and mortality of colorectal cancer(20.49/100 000 and 12.50/100 000)than those of females(15.87/100 000 and 9.68/100 000).The incidence and mortality in urban areas were higher those of that in rural areas.The overall incidence and mortality of colorectal cancer in Gansu province from 2009 to 2015 showed a decreased trend(APC=-8.9,t=-3.0,P<0.05;APC=-0.9,t=-0.3,P=0.8).The incidence trend was statistically significant,and no significant mortality trend have been observed.Conclusion The incidence and mortality of colorectal cancer in Gansu province are relatively high.The assessment of high-risk population for colorectal cancer should be increased,and early screening should be implemented to reduce the incidence and mortality of colorectal cancer.

Key words: Colorectal cancer, Incidence, Mortality, Trend, Cancer registration, Gansu

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