实用肿瘤学杂志 ›› 2021, Vol. 35 ›› Issue (6): 542-546.doi: 10.11904/j.issn.1002-3070.2021.06.011

• 综述 • 上一篇    下一篇

鼻咽癌的免疫治疗研究进展

杨开炎1,2, 韦永昌2, 杨秋云2 综述, 唐凤珠3 审校   

  1. 1.广西中医药大学瑞康临床医学院(南宁 530000);
    2.广西百色市人民医院耳鼻咽喉头颈外科;
    3.广西壮族自治区人民医院耳鼻咽喉头颈外科
  • 收稿日期:2020-12-29 修回日期:2021-02-04 出版日期:2021-12-28 发布日期:2021-12-17
  • 通讯作者: 杨开炎,E-mail:19447620@qq.com
  • 作者简介:杨开炎,男,(1980-),硕士,副主任医师,从事头颈肿瘤的研究。
  • 基金资助:
    百色市科技计划项目(编号:百科计20161501)

Research progress in immunotherapy of nasopharyngeal carcinoma

YANG Kaiyan1,2, WEI Yongchang2, YANG Qiuyun2, TANG Fengzhu3   

  1. 1. Ruikang Clinical Faculty of Guangxi University of Chinese Medicine,Nanning 530000,China;
    2. Department of Otorhinolaryngology,Head and Neck Surgery,People′s Hospital of Guangxi Baise;
    3. Department of Otorhinolaryngology Head and Neck Surgery,People′s Hospital of Guangxi Zhuang Autonomous Region
  • Received:2020-12-29 Revised:2021-02-04 Online:2021-12-28 Published:2021-12-17

摘要: 鼻咽癌是中国南方地区发病率较高的恶性肿瘤,鼻咽癌的治疗目前以同步放化疗为主要治疗方式,早期鼻咽癌的预后较好,而晚期鼻咽癌的预后较差。免疫治疗作为一种治疗恶性肿瘤的新方法,在临床上应用越来越广泛,并在一些恶性肿瘤的治疗上取得较好效果,成为目前临床研究热点。本文对免疫治疗应用在鼻咽癌方面的研究进行综述,以发现存在的问题和新的研究方向。

关键词: 鼻咽癌, 免疫疗法, 细胞免疫治疗, 单克隆抗体, 肿瘤疫苗

Abstract: Nasopharyngeal carcinoma is a malignant tumor with a high incidence in southern China.The treatment of nasopharyngeal carcinoma currently uses concurrent radiotherapy and chemotherapy as the main treatment.The prognosis of early nasopharyngeal carcinoma is better,while the prognosis of advanced nasopharyngeal carcinoma is poor.As a new method of treating malignant tumors,immunotherapy is more and more widely used clinically.It has achieved good results in the treatment for some malignant tumors,and has become a current clinical research hotspot.This article reviews the application of immunotherapy in nasopharyngeal carcinoma in order to discover existing problems and new research directions.

Key words: Nasopharyngeal carcinoma, Immunotherapy, Cellular immunotherapy, Monoclonal antibody, Tumor vaccines

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