肝细胞癌相关RNA结合蛋白研究进展

doi:10.11904/j.issn.1002-3070.2021.06.018

实用肿瘤学杂志 ›› 2021, Vol. 35 ›› Issue (6): 576-579.doi: 10.11904/j.issn.1002-3070.2021.06.018

肝细胞癌相关RNA结合蛋白研究进展

赵浩然, 李满综述, 张玉宝审校

哈尔滨医科大学附属肿瘤医院肝胆外科(哈尔滨 150081)

收稿日期:2020-11-19 修回日期:2021-03-05 出版日期:2021-12-28 发布日期:2021-12-17
通讯作者: 张玉宝,E-mail:zhyb88077@sina.com
作者简介:赵浩然,男,(1994-),硕士研究生,从事肝胆胰肿瘤的诊断及外科治疗的研究。

Research progress of hepatocellular carcinoma-related RNA binding protein

ZHAO Haoran, LI Man, ZHANG Yubao

Department of Hepatobiliary Surgery,Harbin Medical University Cancer Hospital,Harbin 150081,China

Received:2020-11-19 Revised:2021-03-05 Online:2021-12-28 Published:2021-12-17

摘要/Abstract

摘要： 原发性肝癌在中国的发生率及死亡率多年以来一直稳居恶性肿瘤的前五位,且复发率高,预后不良。近些年,随着人们对基因表达与癌症发生发展相关研究的不断深入,探索范围已不仅仅局限于编码RNA的研究,许多非编码RNA在恶性肿瘤进展过程中的作用也逐步引起了研究者们的重视,其中RNA结合蛋白作为参与这些RNA调控的“交通枢纽”起到了至关重要的作用。本文将针对肝细胞癌相关的RNA结合蛋白研究进展进行阐述,旨在为今后的研究提供有价值的参考及思路。

关键词: 肝细胞癌, RNA结合蛋白, 研究进展

Abstract: The incidence and mortality of primary liver cancer in China have been among the top five malignant tumors for many years,the recurrence rate is high and the prognosis is poor.In recent years,with the continuous in-depth research on gene expression,carcinogenesis and development,the scope of exploration is not limited to the study of coding RNA.Many non-coding RNAs have been gradually attracted the attention of researchers.RNA binding proteins,as the“transportation hub”involved in the regulation of these RNAs,play an important role.This article will describe the research progress of RNA-binding proteins related to hepatocellular carcinoma one by one,in order to provide valuable references and ideas for future research.

Key words: Hepatocellular carcinoma, RNA binding proteins, Research progress

中图分类号:

R735.7

赵浩然, 李满, 张玉宝. 肝细胞癌相关RNA结合蛋白研究进展[J]. 实用肿瘤学杂志, 2021, 35(6): 576-579.

ZHAO Haoran, LI Man, ZHANG Yubao. Research progress of hepatocellular carcinoma-related RNA binding protein[J]. Journal of Practical Oncology, 2021, 35(6): 576-579.

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链接本文: http://journal09.magtechjournal.com/Jwk3_syzlxzz/CN/10.11904/j.issn.1002-3070.2021.06.018

http://journal09.magtechjournal.com/Jwk3_syzlxzz/CN/Y2021/V35/I6/576

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肝细胞癌相关RNA结合蛋白研究进展

Research progress of hepatocellular carcinoma-related RNA binding protein

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