实用肿瘤学杂志 ›› 2023, Vol. 37 ›› Issue (3): 195-199.doi: 10.11904/j.issn.1002-3070.2023.03.001

• 癌情监测 •    下一篇

沧州市区2010—2019年甲状腺癌发病时间趋势和生存分析

高哲敏1, 李晓雪1, 霍恺2, 王立彬1, 陈静1, 鲁文慧1   

  1. 1.沧州市疾病预防控制中心(沧州 061000);
    2.沧州市人民医院
  • 收稿日期:2021-12-27 修回日期:2023-05-04 出版日期:2023-06-28 发布日期:2023-08-07
  • 通讯作者: 鲁文慧,E-mail:947958660@qq.com
  • 作者简介:高哲敏,女,(1988-),本科,主管医师,从事慢性病疾病预防控制的研究。
  • 基金资助:
    河北省卫生健康委员会科研基金项目(20200279)

Incidence time trend and survival analysis of thyroid cancer in Cangzhou urban area from 2010 to 2019

GAO Zhemin1, LI Xiaoxue1, HUO Kai2, WANG Libin1, CHEN Jing1, LU Wenhui1   

  1. 1. Cangzhou Center for Disease Control and Prevention,Cangzhou 061000,China;
    2. Cangzhou People's Hospital
  • Received:2021-12-27 Revised:2023-05-04 Online:2023-06-28 Published:2023-08-07

摘要: 目的 对沧州市区2010—2019年居民甲状腺癌发病时间趋势和生存分析进行研究,为沧州市区甲状腺癌的防治工作提供参考。方法 收集2010—2019年沧州市区甲状腺癌发病的监测数据,统计甲状腺癌发病率、标化率、发病率的年度变化百分比(APC)、平均生存时间、累积生存率等。结果 沧州市区2010—2019年甲状腺癌平均年发病率为18.64/10万,中标率为17.60/10万。女性发病率高于男性(P<0.05)。20~岁以上组发病率快速升高,在50~岁组达到峰值,后随年龄增加发病率逐渐下降。2010—2014年,甲状腺癌发病率呈上升趋势(APC=41.95%,95% CI:3.68%~94.35%,P=0.035)。甲状腺癌患者平均生存时间为124.29个月,5年、10年累积生存率分别为93.2%、90.4%。不同性别间生存曲线无统计学差异(P>0.05),65岁以下患者组甲状腺癌生存状况较65岁及以上患者组更好(P<0.05)。结论 甲状腺癌对沧州市区居民的健康威胁日益加重,应通过综合干预手段减轻因甲状腺癌导致的居民疾病和经济负担。

关键词: 甲状腺癌, 发病率, 年度变化百分比, 时间趋势分析, 生存分析

Abstract: Objective This study aimed to study the incidence time trend and survival analysis of thyroid cancer among residents in Cangzhou urban area from 2010 to 2019,so as to provide reference for the prevention and treatment of thyroid cancer in Cangzhou urban area. Methods The surveillance data of thyroid cancer incidence in Cangzhou urban area from 2010 to 2019 were collected,and the incidence,age-standardized rate,annual percentage change in incidence(APC),average survival time and cumulative survival rate of thyroid cancer were analyzed. Results The average annual incidence of thyroid cancer in Cangzhou urban area from 2010 to 2019 was 18.64/100,000,and the China standardized rate was 17.60/100,000.The incidence in female was higher than that in male(P<0.05).The incidence increased rapidly in the 20-year-old group,reaching the peak in the 50-year-old group,and then the incidence gradually decreased with the increase of age.The incidence of thyroid cancer showed an upward trend from 2010 to 2014(APC=41.95%,95% CI:3.68%-94.35%,P=0.035).The average survival time of thyroid cancer patients was 124.29 months,and the 5-year and 10-year cumulative survival rates were 93.2% and 90.4%,respectively.There was no statistical difference in the survival curve between different genders(P>0.05),and the survival status of thyroid cancer in the group of patients under 65 years old was better than that in the group of patients aged 65 and above.(P<0.05). Conclusion Thyroid cancer has a growing threat to the health of residents in Cangzhou urban area.The population′s disease and economic burden of residents caused by thyroid cancer should be taken to reduce through comprehensive intervention measures.

Key words: Thyroid cancer, Incidence, Annual percentage change, Time trend analysis, Survival analysis

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