PRACTICAL ONCOLOGY JOURNAL ›› 2015, Vol. 29 ›› Issue (4): 305-310.doi: 10.11904/j.issn.1002-3070.2015.04.004

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The relationship between clincopathological features and prognosis of colorectal cancer in synchronous liver metastases after resection of the primary tumors

ZHU Mengxiu,LOU Changjie,LI Xiaoxue,LU Haibo   

  1. Department of Medical Oncology,The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081,China
  • Received:2015-03-29 Online:2015-08-27 Published:2015-08-27

Abstract: Objective To analyze the clincopathological features and prognosis of 77 colorectal cancer patients with synchronous liver metastases after resection of the primary tumors.Methods Seventy seven colorectal cancer patients with synchronous liver metastases who underwent resection of the primary tumors and pathological confirmed were enrolled in this retrospective study.The clincopathological features and prognosis were analyzed.Kaplan-Meier method was used to analyze survival rate.The differences between survival curves were calculated by Log-rank test.Results The analysis showed that sex,tumor differentiation and TNM stage were associated with prognosis(P<0.05).The analyses demonstrated no differences in age,primary tumor site,treatment,number of liver metastases and extrahepatic metastasis(P>0.05).There was a significant correlation between CEA,CA19-9 level and gender,tumor differentiation and TNM stage(P<0.001)and the corresponding surgical procedure and TNM stage(P<0.05).Conclusion The analysis show that male,the low differentiation and stage Ⅲ are poor prognosis factors.

Key words: Colorectal carcinoma, Hepatic metastasis, Clincopathological features, Prognosis

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