Abstract: Orbital metastases rarely occur in the patients with cancer,especially from a primary pancreatic carcinoma.In patients presenting ophthalmologic symptoms such as local pain and periorbital edema,it is important to consider orbital metastatic disease.And it is also crucial to determine the site of the primary tumor for better treatments.The mechanism underlying the orbital metastasis from pancreatic carcinoma remains to be clarified.In this report,we describe the clinical characteristics of a case with orbital and hepatic metastases from primary pancreatic carcinoma,providing a reference for clinical diagnosis.Computed tomography of the abdomen and left orbit,in combination with intraorbital biopsy,suggesting a primary pancreatic malignancy with metastatic disease.Surgical pathology and histopathological examination Results confirmed the diagnosis.After single agent gemcitabine chemotherapy,the patient′s symptoms relieved.

Key words: Pancreatic carcinoma, Orbital metastasis, Liver metastasis