PRACTICAL ONCOLOGY JOURNAL ›› 2017, Vol. 31 ›› Issue (5): 472-476.doi: 10.11904/j.issn.1002-3070.2017.05.017

• Review • Previous Articles     Next Articles

Current status of anti-angiogenesis therapy for non-small cell lung cancer

DAI Xin, ZHANG Daxin   

  1. Department of Oncology,First Affiliated Hospital of Harbin Medical University,Harbin,150001,China.
  • Received:2017-02-06 Online:2017-10-28 Published:2017-10-24

Abstract: Angiogenesis is the physiological process of generating new blood vessels from existing networks.In the tumor microenvironment,the dynamic balance of a growing tumor facilitates the transition to persistent angiogenesis.Antiangiogenic drugs have been used in a variety of solid tumors,including lung cancers,by resisting tumor angiogenesis and inhibiting tumor growth,since human recognized its ability.In this paper,recent research status of tumor angiogenesis and non-small cell lung cancer anti-angiogenesis are reviewed in details.

Key words: Anti-angiogenesis, Non-small cell lung cancer, VEGF, TKI

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