Abstract: Objective The aims of this study were to investigate the incidence,death characteristics and time trends of cervical cancer from 2011 to 2015 in the cancer registration areas of Yunnan province,and to provide suggestions for the prevention and treatment of cervical cancer.Methods The incidence and death cases of cervical cancer(ICD-10 code:C53)in the cancer registration areas of Yunnan province from 2011 to 2015 were collected and sorted out.The cervical cancer incidence,mortality,standardized incidence rate,standardized mortality rate,truncated rate,cumulative rate(0~74 years old),and annual percentage change(APC)of trend changes in urban and rural areas were statistically analyzed.Results From 2011 to 2015,the crude incidence of cervical cancer in the cancer registration areas of Yunnan province was 17.39/100,000,the age-standardized incidence rate by Chinese population(ASIR China)was 16.41/100,000,the age-standardized incidence by World population(ASIR World)was 12.41/100,000,the cumulative rate(0~74 years old)was 1.27%,and the truncated rate(35~64 years)was 30.28/100,000.The incidence in rural areas was 22.54/100,000,ASIR China was 22.01/100,000,and the incidence in urban area was 14.65/100,000,ASIR China was 13.60/100,000.The crude mortality of cervical cancer in Yunnan cancer registration areas from 2011 to 2015 was 5.14/100,000,the age-standardized mortality rate by China population(ASMR China)was 4.68/100,000,the age-standardized mortality rate by world population(ASMR World)was 3.56/100,000,the cumulative rate(0~74 years old)was 0.39%,and the truncated rate(35~64 year)was 8.87/100,000.The mortality in rural areas was 7.73/100,000,ASMR China was 7.50/100,000,and the mortality in urban area was 3.77/100,000,ASMR China was 3.31/100,000.The age-specific incidence and mortality were at a low level at 0-24 years of age,and rapidly increased after 25 years of age.The APC for incidence and mortality were-1.4 and 5,respectively,and the APC for ASIR China and ASMR China were-29.8 and 0.1,respectively.There was no statistically difference in the trend of change(P＞0.05).Conclusion The incidence and mortality of cervical cancer in the cancer registration areas of Yunnan province from 2011 to 2015 were higher than that of the national and western regions,especially in rural areas.The annual changes in incidence and mortality had not obvious upward or downward trend.The tertiary prevention work of cervical cancer should be done well,especially in rural areas.

Key words: Cancer registration, Cervical cancer, Incidence, Mortality, Time trend, Yunnan