Journal of Practical Oncology ›› 2021, Vol. 35 ›› Issue (3): 258-262.doi: 10.11904/j.issn.1002-3070.2021.03.012

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Exploration of “immunotherapy moving forward” for digestive system tumors

MA Mingrui, LIAN Jie, LIU Chao, LOU Changjie, ZHANG Yanqiao   

  1. Department of Gartrointestinal Medical Oncology,Harbin Medical University Cancer Hospital,Harbin 150081,China
  • Received:2020-06-15 Revised:2020-09-08 Online:2021-06-28 Published:2021-06-22

Abstract: The emergence of immunosuppressive checkpoint inhibitors has brought new hope for tumor treatment.Immune checkpoint inhibitors need to activate autoimmune anti-tumor cells,so immunotherapy may bring more benefits to patients when their immune status is better.At present,immunotherapy is mostly used for the posterior line treatment of tumor,but the patients after multi-line treatment are generally in poor condition,and the effect of immunotherapy may be reduced.“Immunotherapy forward” refers to the application of immunotherapy in the process of tumor treatment in order to achieve better therapeutic effects.This article reviews the background,clinical trials and problems to be solved of “immunotherapy forward” in digestive system tumors.

Key words: Digestive system tumor, Immune checkpoint inhibitors, Immunotherapy

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