肿瘤相关中性粒细胞与胰腺癌关系的研究进展

doi:10.11904/j.issn.1002-3070.2022.05.012

Abstract

Abstract: Pancreatic cancer is a malignant tumor of digestive system with hidden onset and poor prognosis,which is characterized by difficult early diagnosis and short survival time in the advanced stage.The tumor microenvironment(TME)of pancreatic cancer is often accompanied by the infiltration of a large number of immune cells.As an important part of the TEM,tumor-associated neutrophils(TANs)play an important role in the process of tumor.Relevant studies have shown that TANs play multiple roles in the TME of pancreatic cancer.This article reviews the relationship between TANs and pancreatic cancer to provide ideas for understanding the pathogenesis of pancreatic cancer and proposing new therapies.

Key words: Pancreatic cancer, Tumor-associated neutrophils, Tumor microenvironment, Immunotherapy

CLC Number:

R735.9

LI Xiong, JIANG Wenkai, LANG Zekun, RUI Shaozhen. Research progress on the relationship between tumor-associated neutrophils and pancreatic cancer[J]. Journal of Practical Oncology, 2022, 36(5): 458-462.

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URL: http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/10.11904/j.issn.1002-3070.2022.05.012

http://journal09.magtechjournal.com/Jwk3_syzlxzz/EN/Y2022/V36/I5/458

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Research progress on the relationship between tumor-associated neutrophils and pancreatic cancer

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